184159-44-2Relevant articles and documents
An approach towards the synthesis of oligomers containing a N-2-hydroxyethyl-aminomethylphosphonate backbone: A novel PNA analogues
Van Der Laan, Alexander C.,Stroemberg, Roger,Van Boom, Jacques H.,Kuyl-Yeheskiely, Esther,Efimov, Vladimir A.,Chakhmakhcheva, Oksana G.
, p. 7857 - 7860 (1996)
A convenient route to the preparation of 4-methoxy-1-oxido-pyridine-2-methyl N-2-(4,4'-dimethoxytrityloxy)ethyl-N-thymin-1-yl aminomethylphosphonate (1a T*) and the corresponding N4-benzoylcytosin-1-yl derivative 1b (C*) is reported. The PPNA monomers proved to be suitable building blocks in a solid-support synthesis of the tetradecameric fragment (C*T*T*T*C*T*T*T*T*C*T*C*T*)dT.