18440-21-6

Basic information

• Product Name: N,N′,1,3-TETRAPHENYL-1,3,2,4-DIAZADIPHOSPHETIDINE-2,4-DIAMINE
• CAS NO: 18440-21-6
• Molecular Formula: C₂₄H₂₂N₄P₂
• Molecular Weight: 428.413
• Mol File: 18440-21-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 534.4°Cat760mmHg
• Flash Point: 277°C
• Density: g/cm³
• CAS DataBase Reference: N,N′,1,3-TETRAPHENYL-1,3,2,4-DIAZADIPHOSPHETIDINE-2,4-DIAMINE (CAS DataBase Reference)
• NIST Chemistry Reference: N,N′,1,3-TETRAPHENYL-1,3,2,4-DIAZADIPHOSPHETIDINE-2,4-DIAMINE (18440-21-6)
• EPA Substance Registry System: N,N′,1,3-TETRAPHENYL-1,3,2,4-DIAZADIPHOSPHETIDINE-2,4-DIAMINE (18440-21-6)

Safety Data

• Safety Statements: Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOsub xmlns="">x/sub> and POsub xmlns="">x/sub>.
• Hazardous Substances Data: 18440-21-6(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 39652-39-6 2,4-dichloro-1,3-diphenyl-cyclodiphosphazane 
• 108-88-3 toluene 
• 7719-12-2 phosphorus trichloride 
• 683-85-2 N,N-dimethylaminodichlorophosphane 
• 64945-24-0 2,2,6,6-tetramethylpiperidinodichlorophosphine 
• 79957-32-7 [(PhNH)PNPh]3 

Downstream Products

• 4746-61-6 glycolanilide 
• 6833-04-1 N,N'-Diphenylpimelamide 
• 15510-09-5 Succinanilid 
• 3056-73-3 N-phenylcinnamamide 
• 620-81-5 N,N'-Diphenyloxamid 
• 93-98-1 N-phenyl benzoyl amide 
• 92-77-3 2,3-oxynaphthoic acid phenylamide 
• 3460-11-5 4-nitrobenzanilide 
• 87-17-2 salicylanilide 
• 637-54-7 N-phenylstearamide 
• 77500-28-8 N,N'-diphenyl-fumaramide 
• 620-71-3 N-(phenyl)-2-methylacetamide 
• 103-84-4 Acetanilid 
• 4424-17-3 2-aminobenzanilide 

Relevant articles and documents

Suzuki-Miyaura cross-coupling reactions in water using in situ generated palladium(II)-phosphazane complexes

The phosphazane derivatives (L1-3) were readily obtained by reaction of different ratios of PCl3 and PhNH2. The L 1-3 derivatives were found to be efficient ligands in the palladium-catalyzed Suzuki CC coupling reactions in water. It was determined that with the use of L1-3/Pd(OAc)2 system as a catalyst, aryl halides undergo Suzuki cross-couplings with arylboronic acids to give the desired products in moderate to excellent yields.

1,3,2,4-Diazadiphosphetidines as new P-N ligands for palladium-catalyzed Heck reaction in water

1,3,2,4-Diazadiphosphetidine-based phosphazane class have been used as a new generation of heterogeneous bidentate P(III) ligands containing nitrogen for base-free Pd(II) catalyzed C-C bond formation through Heck coupling reaction of aryl iodides, bromides and chlorides in water with styrene, n-butyl acrylate, 1-octene, and cyclohexene. The reactions occur heterogeneously in water and homogenously or partially heterogeneously in appropriate organic solvents. The ligand together with its Pd(0) complex is easily separated by filtration and reused for several runs.

Synthesis of 3: A Participant in a Phosphorus(III)-Nitrogen Compound Trimer-Dimer Intrerconversion Reaction

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