184534-53-0Relevant academic research and scientific papers
Solid-state synthesis of 4-[(indol-3-yl)-arylmethyl]-1-phenyl-3-methyl-5- pyrazolones by catalysis of molecular iodine
Xia, Min,Lu, Yuedong
, p. 2389 - 2399 (2007/10/03)
4-[(Indol-3-yl)-arylmethyl]-1-phenyl-3-methyl-5-pyrazolones could be smoothly and effectively obtained in good yields through the iodine-catalyzed reactions under solid-state conditions at room tempertaure. The three-component approach in a one-pot proced
The solid-state Michael addition of indole to 4-arylidene-3-methyl-5- pyrazolone
Li, Xiao-Liu,Wang, Yong-Mei,Matsuura, Teruo,Meng, Ji-Ben
, p. 697 - 701 (2007/10/03)
The Michael addition reactions of indole to 4-arylidene-3-methyl-1- phenyl-5-pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1-aryl-1-(3-indolyl)-1-(3'-methyl-1'-phenyl-5'-pyrazolon- 4'-yl)methanes 2, were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon.
The Solid-State Michael Addition of 3-Methyl-1-phenyl-5-pyrazolone
Li, Xiao-Liu,Wang, Yong-Mei,Tian, Bing,Matsuura, Teruo,Meng, Ji-Ben
, p. 129 - 134 (2007/10/03)
A novel solid-state Michael addition between pyrazolone 1 and 4-arylidenepyrazolones 2 at ambient temperature produced Michael adducts, 4,4′-arylidenebis(3-methyl-1-phenyl-5-pyrazolones) 3. Pyrazolones 3 formed salts 4 with Cu2+ in solution, indicating the enolic structure of the pyrazolone rings. The reactivity of 2 with 1 is discussed in terms of the electronic and steric effects of the substituent on the arylidene group of compounds 2. Pyrazolone 1 also underwent the solid state Michael addition reaction with maleimide at 100° to give the adducts 7, 8 and 9.
