1846-67-9

Basic information

• Product Name: 2-Heptynal
• Synonyms: 2-Heptynal
• CAS NO: 1846-67-9
• Molecular Formula: C₇H₁₀O
• Molecular Weight: 110.15
• Mol File: 1846-67-9.mol
• Article Data: 27

Chemical Properties

• Melting Point: -48.35°C (estimate)
• Boiling Point: 196.47°C (estimate)
• Flash Point: 59.2°C
• Appearance: /
• Density: 0.9023 (estimate)
• Vapor Pressure: 1.25mmHg at 25°C
• Refractive Index: 1.4171 (estimate)
• CAS DataBase Reference: 2-Heptynal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Heptynal(1846-67-9)
• EPA Substance Registry System: 2-Heptynal(1846-67-9)

Safety Data

• Hazardous Substances Data: 1846-67-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H10O/c1-2-3-4-5-6-7-8/h7H,2-4H2,1H3

Upstream product

• 32359-01-6 hexenylmagnesium bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 110-62-3 pentanal 
• 73383-23-0 1,1-dibromo 1-hexene 
• 558-13-4 carbon tetrabromide 
• 64576-89-2 1-(1-Ethoxyethoxy)-2-heptyne 
• 58930-68-0 hept-2-ynyl tetrahydropyranyl ether 
• 109-94-4 formic acid ethyl ester 
• 693-02-7 hex-1-yne 
• 64-19-7 acetic acid 
• 18229-78-2 2-hexynyl aldehyde diethyl acetal 
• 91508-87-1 di-hex-1-ynyl-magnesium 
• 1002-36-4 hep-2-yn-1-ol 
• 18232-30-9 1,1-diethoxy-2-heptyne 

Downstream Products

• 16000-67-2 meso-7,8-tetradecanediol 
• 16000-65-0 trans-7,8-tetradecanediol 
• 1002-36-4 hep-2-yn-1-ol 
• 679799-65-6 3-hydroxy-1,2-diphenyl-4-nonyn-1-one 
• 679799-64-5 2-ethyl-3-hydroxy-1-phenyl-4-nonyn-1-one 
• 73922-80-2 (R)-(+)-1-phenylhept-2-yn-1-ol 
• 1380794-84-2 (E)-2-phenyl-N-tosylnon-2-en-4-ynamide 

Relevant articles and documents

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A stereoselective synthesis of anti-gamma,delta-alkynyl- and -alkenyl-beta-hydroxy-alpha-amino esters from tin(II) enolates of glycinate.

Condensations between the tin(II) enolate 11 of ethyl N-tosylglycinate and conjugated ynals 12 and ynones 14 are highly diastereoselective, in favour of the anti-isomers 13 and 15; similar reactions of enals and enones 17 show lower but still useful levels of anti-stereoselectivity.

Annullatins series natural product as well as preparation method and application thereof

The invention belongs to the field of medicinal chemistry, and relates to a cordyceps sinensis secondary metabolite Annullatins series natural product as well as a preparation method and application of the cordyceps sinensis secondary metabolite Annullatins series natural product. A total synthesis route is designed and established through experiments, commercially available raw materials are taken as a substrate, and the preparation of Annullatins series natural product is completed through mild reaction. According to the invention, an in-vitro anti-diabetic vascular complication activity test shows that the Annullatins series natural product designed by the invention plays a role in protecting vascular endothelial cells induced by high glucose, and is beneficial to prevention and treatment of diabetic vascular complication clinically. The Annullatins series natural product has a structural general formula shown in the specification.

Palladium-catalyzed oxidative borylation of conjugated enynones through carbene migratory insertion: synthesis of furyl-substituted alkenylboronates

A palladium-catalyzed oxidative borylation reaction of conjugated enynones is developed. This reaction represents a new method for the synthesis of furyl-substituted alkenylboronates. The reaction works well with a series of conjugated enynones. Boryl migratory insertion of the palladium carbene intermediate is proposed as the key step in these transformations.