185-79-5 Usage
Uses
Used in Biochemical Research:
3,3-Pentamethylenediazirine is used as a photolabeling reagent for investigating protein-protein interactions, ligand-receptor binding, and the identification of protein binding sites and active sites. Its ability to form stable covalent bonds with biomolecules upon photolysis makes it a valuable tool in the fields of biochemistry and chemical biology for exploring various biological processes and molecular interactions.
Used in the Study of Protein-Protein Interactions:
In the field of protein-protein interaction studies, 3,3-Pentamethylenediazirine is used as a crosslinking agent to covalently link interacting proteins. This allows researchers to analyze the structural and functional aspects of these interactions, providing insights into the molecular mechanisms underlying various biological processes.
Used in Ligand-Receptor Binding Studies:
3,3-Pentamethylenediazirine is employed as a photolabeling agent in ligand-receptor binding studies. By covalently crosslinking the ligand to its receptor upon UV exposure, researchers can gain a better understanding of the binding affinity, specificity, and structural requirements for ligand-receptor interactions.
Used in Identification of Protein Binding Sites and Active Sites:
In the identification of protein binding sites and active sites, 3,3-Pentamethylenediazirine serves as a photoaffinity probe. Its photolytic reaction enables the labeling of amino acid residues in the vicinity of the binding or active site, facilitating the elucidation of the molecular details of these sites and their role in protein function.
Overall, 3,3-Pentamethylenediazirine's unique photochemical properties and reactivity make it an indispensable tool in the arsenal of biochemical and chemical biology researchers, enabling the investigation of complex molecular interactions and biological processes with high precision and specificity.
Check Digit Verification of cas no
The CAS Registry Mumber 185-79-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,8 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 185-79:
(5*1)+(4*8)+(3*5)+(2*7)+(1*9)=75
75 % 10 = 5
So 185-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H12N2/c1-2-4-6(5-3-1)7-8-6/h7-8H,1-5H2
185-79-5Relevant academic research and scientific papers
Vedenyapina,Kuznetsov,Nizhnikovskii,Strel'tsova,Makhova,Struchkova,Vedenyapin
, p. 2013 - 2015 (2006)
Electrochemical synthesis of pentamethylenediazirine at the Pt/Ti anode was conducted. The reaction is reversible. The rate constants of the direct and reverse processes were estimated. The product and current yields of the target compound approach to 100%.
AGENTS FOR TREATING NEURODEGENERATIVE DISORDERS
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Page/Page column 22, (2013/08/15)
The present invention relates to compounds of formula I, use of these compounds to treat mental and neurological disorders, especially depressions and psychoses of different etiology.. The compounds provided for the treatment of mental and neurological disorders are presented by a general formula I: wherein R, R', Y are as defined in specification or pharmaceutically acceptable salts thereof, solvates thereof such as hydrates, and pharmaceutical compositions containing such compounds.
