18503-48-5Relevant articles and documents
An ultrastable olefin-linked covalent organic framework for photocatalytic decarboxylative alkylations under highly acidic conditions
Bu, Xiubin,Tian, Miao,Wang, Yichen,Wang, Yichun,Yang, Xiaobo
, p. 4272 - 4279 (2021/06/30)
The application of two-dimensional covalent organic frameworks (2D-COFs) as photoredox catalysts offers sustainable alternatives for visible-light-driven organic transformations. However, under highly complicated organic reaction conditions, maintaining their basic structure and photoactivity is always neglected, which impedes their potential in more organic reaction types and industrial use. Herein, we describe a visible-light-driven decarboxylative alkylation of heterocycles catalysed by an olefin-linked covalent organic framework (2D-COF-2) instead of the commonly used precious metal complexes and organic dyes. A wide range of alkylated heterocycles were selectively and efficiently synthesized under heterogeneous reaction conditions. Relying on the ultrastability of olefin linkage, 2D-COF-2 maintained its basic structure and photoactivity under highly acidic conditions. Moreover, its streamlining industrial potential was demonstrated in recycling experiments, functionalization of bioactive molecules and scale-up reactions.
Iridium-Catalyzed [4+2] Annulations of β-Keto Sulfoxonium Ylides and o-Phenylenediamines: Mild and Facile Synthesis of Quinoxaline Derivatives
Che, Tong,Kang, Hua-Jie,Peng, Dongming,Shu, Bing,Song, Jia-Lin,Wang, Xiao-Tong,Xie, Hui,Zhang, Luyong,Zhang, Shang-Shi,Zhong, Mei
supporting information, (2020/06/25)
A synthetic method for quinoxaline derivatives from the [4+2] annulation of β-keto sulfoxonium ylides and o-phenylenediamine by using (Cp*IrCl2)2 catalyst is described. This novel protocol features mild reaction conditions, moderate to excellent yields, wide substrate scope, and high functional-group compatibility. Moreover, this cyclization strategy was successfully applied in late-stage modification for structurally complex bioactive compounds.
Nickel-Catalyzed Direct Synthesis of Quinoxalines from 2-Nitroanilines and Vicinal Diols: Identifying Nature of the Active Catalyst
Shee, Sujan,Panja, Dibyajyoti,Kundu, Sabuj
, p. 2775 - 2784 (2020/03/13)
The inexpensive and simple NiBr2/1,10-phenanthroline system-catalyzed synthesis of a series of quinoxalines from both 2-nitroanilines and 1,2-diamines is demonstrated. The reusability test for this system was performed up to the seventh cycle, which afforded good yields of the desired product without losing its reactivity significantly. Notably, during the catalytic reaction, the formation of the heterogeneous Ni-particle was observed, which was characterized by PXRD, XPS, and TEM techniques.
