23269-74-1Relevant academic research and scientific papers
Synthesis of 1-(2-bromo-1-arylethyl)-1H-benzotriazoles via NBS promoted addition of 1H-benzotriazole to alkene: Relevance in benzotriazole ring cleavage
Bose, Priyanka,Singh, Anoop S.,Singh, Mala,Tiwari, Vinod K.
, (2020)
A cost-effective and expeditious one-pot synthesis of 1-(2-bromo-1-arylethyl)-1H-benzotriazoles has been devised by reacting styrene and their derivatives with 1H-benzotriazole in presence of N-bromosuccinimide in anhydrous CH2Cl2 at room temperature. Further, the resulted compounds undergo E2-ellimination to afford the respective 1-(1-aryl-vinyl)-1H-benzotriazoles. At the end, 1-(1-phenylvinyl)-1H-benzotriazoles underwent benzotriazole ring cleavage (BtRC) under free radical condition to produce phenanthridine as the final product.
An organoselenium-catalyzed N1- And N2-selective aza-Wacker reaction of alkenes with benzotriazoles
Sun, Kai,Wang, Qinlin,Wang, Xin,Wu, Lanlan,Xue, Yanru,Zhang, Bing
, p. 4436 - 4439 (2020/05/05)
An organoselenium-catalyzed N1- and N2-selective aza-Wacker reaction of alkenes with benzotriazoles is reported, which provides easy access to N1- and N2-olefinated benzotriazole derivatives. The wide substrate
Ambient benzotriazole ring opening through intermolecular radical addition to vinyltriazole
Su, Yijin,Petersen, Jeffrey L.,Gregg, Tesia L.,Shi, Xiaodong
supporting information, p. 1208 - 1211 (2015/03/14)
Radical addition to vinyltriazole was developed as a new approach to achieve 1,2,3-triazole ring opening under mild conditions. Through reagent control, excellent chemoselectivity was achieved, giving either nitrile under basic conditions or quinoxaline under neutral conditions. Reactivities made this method an attractive new reaction mode.
Highly efficient synthesis of vinyl substituted triazoles by Au(I) catalyzed alkyne activation
Duan, Haifeng,Yan, Wuming,Sengupta, Sujata,Shi, Xiaodong
supporting information; experimental part, p. 3899 - 3902 (2010/03/25)
Au(I) catalyzed 1,2,3-triazole addition to non-activated alkyne was reported. A large group of substituted NH-1,2,3-triazoles were suitable for this transformation along with both internal and terminal alkynes. The N-1 and N-2 vinyl substituted 1,2,3-tria
Benzyne click chemistry: Synthesis of benzotriazoles from benzynes and azides
Shi, Feng,Waldo, Jesse P.,Chen, Yu,Larock, Richard C.
supporting information; experimental part, p. 2409 - 2412 (2009/05/11)
(Chemical Equation Presented) A variety of substituted benzotriazoles have been prepared by the [3 + 2] cycloaddition of azides to benzynes. The reaction scope is quite general, affording a rapid and easy entry to substituted, functionalized benzotriazoles under mild conditions.
