18504-86-4

Basic information

• Product Name: 2H-pyrido[4,3-b][1,4]thiazin-3(4H)-one
• CAS NO: 18504-86-4
• Molecular Formula: C₇H₆N₂OS
• Molecular Weight: 166.2003
• Mol File: 18504-86-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 399.2°C at 760 mmHg
• Flash Point: 195.3°C
• Density: 1.367g/cm³
• Vapor Pressure: 1.39E-06mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 2H-pyrido[4,3-b][1,4]thiazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-pyrido[4,3-b][1,4]thiazin-3(4H)-one(18504-86-4)
• EPA Substance Registry System: 2H-pyrido[4,3-b][1,4]thiazin-3(4H)-one(18504-86-4)

Safety Data

• Hazardous Substances Data: 18504-86-4(Hazardous Substances Data)

Upstream product

• 89002-13-1 3-amino-4-mercaptopyridine 
• 79-04-9 chloroacetyl chloride 
• 2365-48-2 Methyl thioglycolate 
• 105752-11-2 4-iodopyridin-3-amine 
• 31872-62-5 4-methoxy-3-nitro-pyridine 
• 18504-85-3 4-Carboxymethylthio-3-nitropyridine 
• 20511-15-3 3-amino-4-chloropyridine 
• 758-08-7 Thioglycolamide 

Relevant articles and documents

Facile synthesis of 1,4-benzothiazin-3-ones from Cu-catalyzed coupling of 2-iodoanilines and 2-mercaptoacetate

A novel synthesis of 1,4-benzothiazin-3-ones was developed from Cu-catalyzed coupling of readily available substituted 2-iodoanilines with 2-mercaptoacetate. The new method offers clear advantages over existing approaches for its one-step simple operation, wider reaction scope, and moderate to excellent isolated yields.

The Synthesis of Pyridothiazinones

Both 2 and 4 halogenated 3-aminopyridines react thermally with α-mercapto esters and amides to afford pyrido and pyridothiazinones.N-alkylation and oxidation of the products were investigated.

Syntheses in the group of pyridothiazinones

-