185099-47-2Relevant academic research and scientific papers
Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3- benzyl-2-piperidinones (δ-valerolactams) and hexahydro-2H-azepin-2-ones (ε- caprolactams)
Reddy, P. Amruta,Woodward, Karen E.,McIlheran, Sarah M.,Hsiang, Bonnie C. H.,Latifi, Tammy N.,Hill, Matthew W.,Rothman, Steven M.,Ferrendelli, James A.,Covey, Douglas F.
, p. 44 - 49 (1997)
A series of 3-substituted 2-piperidinone (δ-valerolactam) and hexahydro-2H-azepin-2-one (ε-caprolactam) derivatives were prepared and evaluated as anticonvulsants in mice. In the 2-piperidinone series, 3,3- diethyl compound 7b is the most effective antico
Anticonvulsant and anxiolytic lactam and thiolactam derivatives
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, (2008/06/13)
This invention relates to lactam and thiolactam derivatives having useful anticonvulsant and anxiolytic activity, pharmaceutical compositions containing these compounds and therapeutic applications using such compositions.
