1853-91-4

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-4-METHYL-6-PHENYL-1,3,5-TRIAZINE is used as a building block for the synthesis of pharmaceuticals due to its unique chemical structure and potential biological activity.
Used in Agrochemical Industry:
2-AMINO-4-METHYL-6-PHENYL-1,3,5-TRIAZINE is used as a precursor in the development of agrochemicals, contributing to the creation of new compounds with potential applications in agriculture.
Used as a Reagent in Chemical Reactions:
2-AMINO-4-METHYL-6-PHENYL-1,3,5-TRIAZINE is used as a reagent to facilitate the formation of new compounds in various chemical reactions, expanding its utility in the field of organic chemistry.
Used in Research and Development:
2-AMINO-4-METHYL-6-PHENYL-1,3,5-TRIAZINE is employed in research for its potential applications in medicine and industry, as its biological activity and chemical properties are being explored for innovative uses.

InChI:InChI=1/C10H10N4/c1-7-12-9(14-10(11)13-7)8-5-3-2-4-6-8/h2-6H,1H3,(H2,11,12,13,14)

Upstream product

• 127-19-5 N,N-dimethyl acetamide 
• 50-01-1 guanidine hydrochloride 
• 5333-86-8 ethyl benzimidate hydrochloride 

Relevant academic research and scientific papers

Base-mediated synthesis of unsymmetrical 1,3,5-triazin-2-amines via three-component reaction of imidates, guanidines, and amides or aldehydes

A simple and efficient method for the basemediated synthesis of unsymmetrical 1,3,5-triazin-2-amines has been developed. The protocol uses readily available imidates, guanidines, and amides or aldehydes as the starting materials, cesium carbonate as the base, no catalyst or additive is required, and the three-component reaction provides diverse 1,3,5-triazin-2-amines in moderate to good yields with tolerance of wide functional groups.

Process for the preparation of 2-amino-s-triazines

The present invention relates to a process for the preparation of 2-amino-s-triazines in three stages. In the first stage nitriles, alcohols and hydrogen chloride are reacted to form the corresponding imido-ester hydrochlorides. In the second stage, the imido-ester hydrochlorides are reacted with cyanamide in the aqueous phase to form the N-cyanimido-esters, which comprises carrying out the first stage in the presence of acetic acid esters and the second stage in an aqueous solution which has been brought to a pH value of 5-8 by addition of bases, and reacting the N-cyanimido-esters with O-alkylisourea, S-alkylisothiourea, guanidine or amidine salts in the presence of a base in the third stage. The 2-amino-s-triazines can be prepared in a high purity and with good yields in this manner.