18538-53-9

Basic information

• Product Name: Oxiranecarboxamide, 3-phenyl- (9CI)
• Synonyms: Oxiranecarboxamide, 3-phenyl- (9CI);3-Phenyloxiranecarboxamide
• CAS NO: 18538-53-9
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17326
• Product Categories: AMIDE
• Mol File: 18538-53-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Oxiranecarboxamide, 3-phenyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranecarboxamide, 3-phenyl- (9CI)(18538-53-9)
• EPA Substance Registry System: Oxiranecarboxamide, 3-phenyl- (9CI)(18538-53-9)

Safety Data

• Hazardous Substances Data: 18538-53-9(Hazardous Substances Data)

Upstream product

• 621-79-4 cinnamamide 
• 621-79-4 cinnamamide 
• 683-57-8 bromo-acetic acid amide 
• 100-52-7 benzaldehyde 
• 1885-38-7 cinnamic nitrile 
• 79-07-2 Chloroacetamide 

Downstream Products

• 621-79-4 cinnamamide 
• 5801-57-0 (Z)-2-hydroxy-3-phenyl-acrylic acid 
• 705-59-9 2-hydroxy-3-phenylpropionamide 

Relevant articles and documents

Primary Alcohols via Nickel Pentacarboxycyclopentadienyl Diamide Catalyzed Hydrosilylation of Terminal Epoxides

The efficient and regioselective hydrosilylation of epoxides co-catalyzed by a pentacarboxycyclopentadienyl (PCCP) diamide nickel complex and Lewis acid is reported. This method allows for the reductive opening of terminal, monosubstituted epoxides to form unbranched, primary alcohols. A range of substrates including both terminal and nonterminal epoxides are shown to work, and a mechanistic rationale is provided. This work represents the first use of a PCCP derivative as a ligand for transition-metal catalysis.

5-(α-Halobenzyl)- and 5-Benzylidene-2,2-dimethyl-1,3-oxazolidin-4-ones in Synthesis of α-Hydroxy Acids

The reactions of acid hydrolysis of 5-(α-halobenzyl)- and 5-benzylidene-2,2-dimethyl-1,3-oxazolidin-4-ones were studied. A possibility of the synthesis of corresponding α-hydroxy acids was shown.

Lewis acid-promoted electron transfer deoxygenation of epoxides, sulfoxides, and amine N-oxides: the role of low-valent niobium complexes from NbCl5 and Zn

A mild and operationally simple deoxygenation of epoxides, sulfoxides, and amine N-oxides is described using a sub-stoichiometric amount of low-valent niobium complexes generated in situ from commercially available NbCl5 and zinc dust. The deoxygenation proceeds by a reductive cleavage of polarized O-C/O-N/O-S bonds through a single electron transfer from zinc metal to the niobium-substrate complex due to the high oxophilic nature of the niobium species. The presence of adjacent radical-stabilizing groups is beneficial to epoxide substrates; however the similar prerequisite does not apply to sulfoxides and amine N-oxides, where a broad range of substrates are efficiently deoxygenated in excellent yields.