18545-83-0

Usage

Uses

Used in the Food Industry:
DIETHYL 2-METHYLGLUTARATE is used as a flavoring agent for its distinctive fruity scent, enhancing the taste profiles of various food products.
Used in the Chemical Industry:
DIETHYL 2-METHYLGLUTARATE serves as a solvent in a range of chemical reactions, facilitating processes that require its unique solvency properties.
Used in Pharmaceutical Synthesis:
DIETHYL 2-METHYLGLUTARATE is utilized as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new medications.
Used in Agricultural Chemicals:
It also finds application as an intermediate in the production of agricultural chemicals, contributing to the creation of effective products for crop protection and enhancement.
Given its flammable nature, care must be taken in handling DIETHYL 2-METHYLGLUTARATE, underscoring the need for proper safety measures during its use in these various applications.

InChI:InChI=1/C10H18O4/c1-4-13-9(11)7-6-8(3)10(12)14-5-2/h8H,4-7H2,1-3H3

Upstream product

• 857793-16-9 2-isobutyryl-4-methyl-glutaric acid diethyl ester 
• 141-52-6 sodium ethanolate 
• 18069-17-5 2-methylglutaric acid 
• 5621-43-2 diethyl 2-methyleneglutarate 
• 105-37-3 Ethyl propionate 
• 140-88-5 ethyl acrylate 
• 62718-06-3 2-acetyl-4-methyl-glutaric acid diethyl ester 
• 64-17-5 ethanol 
• 1968-40-7 ethyl 4-pentenoate 
• 201230-82-2 carbon monoxide 
• 1115-81-7 (R)-2-methylglutaric acid 
• 122-51-0 orthoformic acid triethyl ester 
• 598-32-3 2-hydroxy-3-butene 
• 6117-91-5 (E/Z)-2-buten-1-ol 

Downstream Products

• 68428-78-4 2-(2,4-Dimethyl-phenyl)-4-methyl-cyclohexane-1,3-dione 
• 3677-73-4 2-Methyl-1,1,5,5-tetraphenyl-pentan 
• 110724-99-7 2-Ethyl-hexanoic acid 2-(2,4-dimethyl-phenyl)-4-methyl-3-oxo-cyclohex-1-enyl ester 
• 74607-12-8 diethyl β-carboethoxypropylmalonate 
• 42856-62-2 2-methyl-1,5-pentanediol 
• 3677-75-6 2-Methyl-1,1,5,5-tetraphenyl-pentan-1,5-diol 

Relevant academic research and scientific papers

THE MICHAEL REACTION OF SIMPLE ESTER ENOLATES TO α,β-UNSATURATED ESTERS

Lithium enolates generated from simple esters are found readily to add to α,β-unsaturated esters at -78 deg C and glutarates are obtained in high yield.

PROCESS FOR DOUBLE CARBONYLATION OF ALLYL ALCOHOLS TO CORRESPONDING DIESTERS

The invention relates to a process for doubly carbonylating allyl alcohols to the corresponding diesters, wherein a linear or branched allyl alcohol is reacted with a linear or branched alkanol (alcohol) with supply of CO and in the presence of a catalytic system composed of a palladium complex and at least one organic phosphorus ligand and in the presence of a hydrogen halide selected from HCl, HBr and HI.

Palladium complexes with N-heterocyclic carbene ligands as catalysts for the alkoxycarbonylation of olefins

Palladium catalysts, generated from Pd(OAc)2 and 2 equiv of N,N-dialkylbenzimidazolium iodide, are effective for the alkoxycarbonylation of olefins in high yields (>90%). Alkoxycarbonylation of 1-hexene in dimethylacetamide is achieved within 24 h at 110 C using 1 mol % catalyst, 1000 psi CO, and ethanol. Reactions can be prepared in air, without the need of an acid additive to produce ethyl 2-methylhexanoate and ethyl heptanoate in approximately a 2:1 ratio.

Electrochemical deacetylation of 1,3-dicarbonyl compounds

Mild deacetylation of 1,3-dicarbonyl compounds was achieved by halonium-ion mediated electrolysis. In this reaction, the supporting electrolyte including sodium halide NaX (X = Cl or Br) was essential since the reaction proceeded through substitution by a halonium ion, generated electrochemically at anode, on active methine carbons followed by base-aitalyzed deacctylation, and was terminated by reductive dehalogenation of the formed α-halo carbonyl compounds at cathode.

The Circular Dichroism of (-)-(S)-3-Methylthian: a Study of the Electronic Transitions and Stereochemistry of Cyclic Sulphur Derivatives

The u.v. and c.d. spectra of (-)-(S)-3-methylthian and the u.v., l.d., and m.c.d. spectra of thian have been analysed by means of non-empirical MO calculations.While the n?* assignment of the transition at ca. 232 nm is confirmed, the absorption at ca. 214 nm is assigned to a ??* (A1A1) transition.The stereochemistry of cyclic sulphur derivatives is discussed in the light of a symmetry rule previously proposed.