185671-80-1Relevant academic research and scientific papers
Synthesis and biological properties of partially modified retro and retro-inverso pseudo peptides of Arg-Gly-Asp (RGD)
Nishikawa, Naoyuki,Komazawa, Hiroyuki,Orikasa, Atsushi,Yoshikane, Mitsuo,Yamaguchi, Jiro,Kojima, Masayoshi,Ono, Mitsunori,Itoh, Isamu,Azuma, Ichiro,Fujii, Hideki,Murata, Jun,Saiki, Ikuo
, p. 2725 - 2728 (1996)
Partially modified retro and retro-inverso peptide analogs of Arg-Gly-Asp (RGD) were synthesized and examined their inhibitory effects on experimental lung metastasis of murine melanoma and adenosine 5'-diphosphate (ADP) induced platelet aggregation. The analogs showed efficient therapeutic potency for the tumor metastasis but low inhibitory effect on ADP induced platelet aggregation.
