Synthesis and biological properties of partially modified retro and retro-inverso pseudo peptides of Arg-Gly-Asp (RGD)

DOI: 10.1016/S0960-894X(96)00494-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2725 - 2728 (1996)

Update date:2022-08-03

Topics:

Authors:

Nishikawa, Naoyuki

Komazawa, Hiroyuki

Orikasa, Atsushi

Yoshikane, Mitsuo

Yamaguchi, Jiro

Kojima, Masayoshi

Ono, Mitsunori

Itoh, Isamu

Azuma, Ichiro

Fujii, Hideki

Murata, Jun

Saiki, Ikuo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(96)00494-5

Partially modified retro and retro-inverso peptide analogs of Arg-Gly-Asp (RGD) were synthesized and examined their inhibitory effects on experimental lung metastasis of murine melanoma and adenosine 5'-diphosphate (ADP) induced platelet aggregation. The analogs showed efficient therapeutic potency for the tumor metastasis but low inhibitory effect on ADP induced platelet aggregation.

Full text of DOI:10.1016/S0960-894X(96)00494-5

Products guided by the article

Product name:C₄₁H₄₅N₅O₁₀S

Cas No:185671-80-1

R&D Labs maybe for 185671-80-1

Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai
JenKem Technology Co., Ltd.

Contact:86-10-62983737; +86-10-51287608

Address:4/F Building C, 2 Shangdi Xinxi Road
Shanghai Run-Biotech Co., Ltd.

website:http://www.run-biotech.com

Contact:+86-21-31576854/57171705 / 57171706

Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China
Antaeus Bio-technology Co., LTD(expird)

Contact:021-31252569

Address:shanghai pudong
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China

Relevant to this article

Scalable, efficient and rapid chemical synthesis of L-Fructose with high purity

Doi:10.1016/j.carres.2019.05.010
(2019)
5-Formyl salicylaldehyde as a linker for the synthesis of benzofuran containing insulin sensitivity enhancer compounds

Doi:10.1016/S0040-4039(97)82938-3
(1996)
Preparation of β'-phenylsulfonyl α,β-unsaturated ketones and unsymmetric dialkenyl ketones from 2-alkenyl-2-methoxycyclopropyl phenyl sulfones

Doi:10.1016/S0040-4039(97)82948-6
(1996)
Doi:10.1007/BF00468349
()
Controlling the orientation of sequential ligands in the self-assembly of binuclear coordination compounds

Doi:10.1021/ja963265f
(1997)
Synthesis of 4,5,6-trisubstituted 3-cyanopyridine-2(1H)-thiones based on α-substituted β-diketones

Doi:10.1007/BF01431119
(1996)

Article Doi