185757-61-3

Upstream product

• 116546-78-2 (S)-1-benzyloxy-2-methylpentan-3-one 
• 100-39-0 benzyl bromide 
• 93877-21-5 1,4-dibenzyloxybut-2-yne 
• 68972-96-3 (Z)-1,4-dibenzyloxy-2-butene 

Downstream Products

• 185757-63-5 (1R,2S,4S)-5-Benzyloxy-1-[(S)-2-((1S,2R)-3-benzyloxy-1-benzyloxymethyl-1,2-dihydroxy-propyl)-oxiranyl]-1-hydroxy-2,4-dimethyl-pentan-3-one 
• 185757-62-4 (2S,4S,5R,7S,8R)-1,9-Bis-benzyloxy-7-benzyloxymethyl-5,7,8-trihydroxy-2,4-dimethyl-6-methylene-nonan-3-one 

Relevant academic research and scientific papers

Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 → 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30.