Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

DOI: 10.1016/S0040-4039(96)02083-7

Source and publish data:

Tetrahedron Letters p. 8803 - 8806 (1996)

Update date:2022-08-03

Topics:

Authors:

Paterson, Ian

Fessner, Klaus

Finlay, M. Raymond V.

Jacobs, Mark F.

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Article abstract of DOI:10.1016/S0040-4039(96)02083-7

Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 → 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30.

Full text of DOI:10.1016/S0040-4039(96)02083-7

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