18600-63-0

Usage

Heterocyclic compound

It contains atoms of at least two different elements in its ring structure.

Naphthalene derivative

It belongs to the class of compounds derived from naphthalene.

Naphtho[2,3-d]oxazine skeleton

A fused tricyclic ring system containing a naphthalene moiety and an oxazine ring.

Phenyl group at 2-position

The compound has a phenyl group attached to the oxazine ring at the 2-position.

Unique structural and chemical properties

The presence of the phenyl group gives the compound distinct characteristics.

Potential applications

4H-Naphth[2,3-d][1,3]oxazin-4-one, 2-phenylmay have uses in organic synthesis, pharmaceuticals, and materials science.

Upstream product

• 495-18-1 Benzohydroxamic acid 
• 98-88-4 benzoyl chloride 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 100-52-7 benzaldehyde 
• 5959-52-4 2-Amino-3-naphthoic acid 
• 113443-62-2 N-methoxy-N-methylnaphthalene-2-carboxamide 

Downstream Products

• 153684-40-3 2-(2'-fluorobenzoyl)-3-(N-benzoylamino)naphthalene 
• 154849-03-3 2--3-(2'-fluorobenzoyl)naphthalene 
• 153684-37-8 2-amino-1-(2'-fluorobenzoyl)naphthalene 
• 153684-46-9 2-(N-benzoylamino)-3-(2'-thienylcarbonyl)naphthalene 

Relevant academic research and scientific papers

Direct synthesis of benzoxazinones via Cp*Co(III)-catalyzed C–H activation and annulation of sulfoxonium ylides with dioxazolones

A highly novel and direct synthesis of benzoxazinones was developed via Cp*Co(III)-catalyzed C–H activation and [3 + 3] annulation between sulfoxonium ylides and dioxazolones. The reaction is conducted under base-free conditions and tolerates various functional groups. Starting from diverse readily available sulfoxonium ylides and dioxazolones, a variety of benzoxazinones could be synthesized in one step in 32%-75% yields.

Oxidative NHC catalysis for base-free synthesis of benzoxazinones and benzoazoles by thermal activated NHCs precursor ionic liquid catalyst using air as oxidant

A reusable thermal activated NHC precursor ionic liquid catalyst ([BMIm]2[WO4]) has been prepared and developed for the synthesis of nitrogen-containing heterocycles such as benzoxazinones and benzoazoles through imines activation. [BMIm]2[WO4] exhibited the good activity for the base-free condensation and oxidative NHC catalysis tandem under air atmosphere. The catalyst can be recovered and reused for at least five runs in gram scale synthesis without any decrease in catalytic activity. Furthermore, the control experiments demonstrated that the reaction involved formation of aromatic aldimines, NHC-catalyzed oxidative formation of imidoyl azoliums and intramolecular cyclization to generate the product.

One-step synthesis of 4H-3,1-benzoxazin-4-ones from Weinreb amides and 1,4,2-dioxazol-5-ones via cobalt-catalyzed C-H bond activation

A one-step synthesis of 4H-3,1-benzoxazin-4-ones from readily available Weinreb amides and 1,4,2-dioxazol-5-ones under Cp*Co(III) catalysis is described. The reactions proceeded in moderate to good yields with high functional group compatibility.