422565-31-9

Upstream product

• 102-92-1 Cinnamoyl chloride 
• 120686-18-2 (S)-3-amino-3-phenylpropionic acid tert-butyl ester 
• 160978-12-1 tert-butyl (S)-3-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoate 
• 357417-35-7 (3S)-3-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoic acid 
• 186179-24-8 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate 
• 78521-64-9 N-(4-aminobutyl)-4-methyl benzenesulfonamide 

Downstream Products

• 422565-32-0 (S)-5,9-bis[(4-methylphenyl)sulfonyl]-4-phenyl-1,5,9-triazacyclotridecan-2-one 
• 65094-32-8 (S)-4-phenyl-9-(3-phenylprop-2-enoyl)-1,5,9-triazacyclotridecan-2-one 
• 126641-91-6 (S)-4-phenyl-1,5,9-triazacyclotridecan-2-one 

Relevant academic research and scientific papers

A novel synthesis of the macrocyclic spermidine alkaloid (+)-(S)-dihydroperiphylline

A novel, short, and highly stereoselective synthesis of the macrocyclic spermidine alkaloid (+)-(S)-dihydroperiphylline (15) is described. The key synthetic steps were the stereoselective addition of the chiral amine 1 to the cinnamate 2 and cyclization o