186315-85-5 Usage
General Description
1,3-DIFLUORO-4-NITRO-2-(TRIMETHYLSILYL)BENZENE is a chemical compound with the molecular formula C9H9F2NO2Si. It is a nitroaromatic compound that contains two fluorine atoms and a trimethylsilyl group attached to a benzene ring. 1,3-DIFLUORO-4-NITRO-2-(TRIMETHYLSILYL)BENZENE is used in organic synthesis as a reagent or building block for creating more complex molecules. The trimethylsilyl group is often used as a protective group for reactive functional groups in organic chemistry, allowing for selective reactions to take place. The presence of the fluorine atoms also makes this compound potentially useful in materials science and pharmaceutical research. Overall, 1,3-DIFLUORO-4-NITRO-2-(TRIMETHYLSILYL)BENZENE is a versatile chemical that has applications in various fields of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 186315-85-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,1 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 186315-85:
(8*1)+(7*8)+(6*6)+(5*3)+(4*1)+(3*5)+(2*8)+(1*5)=155
155 % 10 = 5
So 186315-85-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H11F2NO2Si/c1-15(2,3)9-6(10)4-5-7(8(9)11)12(13)14/h4-5H,1-3H3
186315-85-5Relevant articles and documents
Metalation of Nitroaromatics with in Situ Electrophiles
Black, W. Cameron,Guay, Benoit,Scheuermeyer, Frank
, p. 758 - 760 (1997)
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Electrophilic ipso substitution of trimethylsilyl groups in fluorobenzenes
Coe, Paul L.,Stuart, Alison M.,Moody, David J.
, p. 27 - 32 (2007/10/03)
Using variants of literature methods 2,4- and 2,6- difluorophenyltrimethylsilanes have been bromodesilylated to the corresponding bromodifluorobenzenes in moderate to good yields, 3-bromo-2,6-difluorophenyltrimethylsilane afforded 1,3-dibromo-2,4-difluorobenzene whilst 1,3-difluoro-2,4-bis(trimethylsilyl)benzene yielded 3-bromo-2,6-difluorophenyltrimethylsilane. Application of either the Eaborn or Chvalovsky methods of nitrodesilylation to 4-fluorophenyltrimethylsilane, 2,4-difluorophenyltrimethylsilane and 2,6-difluorophenyltrimethylsilane afforded largely the corresponding desilylated products together with products associated with initial protodesilylation, followed by nitration of the resulting fluorobenzenes. The results obtained show that ipso desilylation in the fluoroaromatic series does follow the expected pattern previously obtained in the hydrocarbon analogues. They also show that in some cases the formation of unusually substituted fluoroarenes can be achieved more readily than by the methods previously used.
