186386-90-3

Basic information

• Product Name: 4-fluoro-2-(2,2,2-trifluoroethoxy)aniline
• Synonyms: 4-fluoro-2-(2,2,2-trifluoroethoxy)aniline
• CAS NO: 186386-90-3
• Molecular Formula: C₈H₇F₄NO
• Molecular Weight: 209.1408928
• Mol File: 186386-90-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-fluoro-2-(2,2,2-trifluoroethoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluoro-2-(2,2,2-trifluoroethoxy)aniline(186386-90-3)
• EPA Substance Registry System: 4-fluoro-2-(2,2,2-trifluoroethoxy)aniline(186386-90-3)

Safety Data

• Hazardous Substances Data: 186386-90-3(Hazardous Substances Data)

Upstream product

• 186386-91-4 4-fluoro-1-nitro-2-(2,2,2-trifluoroethoxy)benzene 
• 446-35-5 2,4-Difluoronitrobenzene 
• 446-36-6 5-fluoro-2-nitrophenol 

Downstream Products

• 186385-74-0 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-5-hydroxymethyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 
• 592527-68-9 5-ethyl-3-(3-{4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 
• 186385-81-9 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propyl)-5-dimethylamino-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione 
• 186385-78-4 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-5-methoxy-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 
• 186385-77-3 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoroethoxy)-phenyl]piperazin-1-yl}propyl)-5-chloro-1-[2-(trimethylsilyl)ethoxymethyl]-2,4(1H,3H)-pyrimidinedione 
• 186385-71-7 3-(3-{4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrimidine-2,4-dione 
• 592527-71-4 1-benzyl-3-(3-{4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-propyl)-6-methyl-1H-pyrimidine-2,4-dione 
• 186386-21-0 RS 100975 
• 186388-11-4 1-(3-chloro-propyl)-4-[4-fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazine 
• 186387-05-3 1-[4-fluoro-2-(2,2,2-trifluoroethoxy)-phenyl]-piperazine 

Relevant articles and documents

AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY

An amino pyrimidine compound for inhibiting protein tyrosine kinase activity, a pharmaceutical composition thereof, preparation therefor, and an application thereof. Specifically, an amino pyrimidine compound represented by formula (I), R1, R2, L, Y, R6, W, A, m, and n being defined in the specification, and a pharmaceutically acceptable salt, a stereoisomer, a solvent compound, a hydrate, a polymorphism, a prodrug, or an isotope variant thereof. The compound can be used for treating and/or preventing protein tyrosine kinase-related diseases such as cell proliferative diseases, cancers, and immune diseases.