18649-65-5

Usage

InChI:InChI=1/C10H19N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h8-10H,1-7,11H2

Upstream product

• 15876-37-6 2-Oxo-trans-decalin-oxim 
• 64-17-5 ethanol 
• 91716-73-3 β-decalone oxime 
• 3275-10-3 cis,trans-2-decalyl tosylate 
• 64-19-7 acetic acid 
• 13032-41-2 (+/-)-(4ar,8ac)-decahydro-[2t]naphthoic acid 
• 109093-05-2 (2RS,4aSR,8aRS)-N-(decahydronaphthalen-2-yl)benzamide 
• 93-09-4 naphthalene-2-carboxylate 
• 7647-01-0 hydrogenchloride 
• 936-35-6 (+/-)-(4ar,8ac)-decahydro-[2c]naphthylamine 
• 91-59-8 naphthalen-2-ylamine 

Downstream Products

• 49784-94-3 (4aR)-2c-acetylamino-(4arH.8atH)-decahydro-naphthalene 
• 109093-05-2 (4aR)-2c-benzamino-(4arH.8atH)-decahydro-naphthalene 
• 936-35-6 (+)-(4ar,8ac)-decahydro-[2c]naphthylamine 
• 936-35-6 (-)-(4ar,8ac)-decahydro-[2c]naphthylamine 
• 49784-94-3 2-acetylamino-decahydro-naphthalene 
• 109093-05-2 2-benzamino-decahydro-naphthalene 
• 137795-76-7 (R)-4-Benzyloxycarbonylamino-4-(decahydro-naphthalen-2-ylcarbamoyl)-butyric acid benzyl ester 
• 91-17-8 decalin 
• 60976-10-5 N-decahydro[2]naphthyl-acetamide 

Relevant academic research and scientific papers

Chemoselective and Tandem Reduction of Arenes Using a Metal–Organic Framework-Supported Single-Site Cobalt Catalyst

The development of heterogeneous, chemoselective, and tandem catalytic systems using abundant metals is vital for the sustainable synthesis of fine and commodity chemicals. We report a robust and recyclable single-site cobalt-hydride catalyst based on a porous aluminum metal–organic framework (DUT-5 MOF) for chemoselective hydrogenation of arenes. The DUT-5 node-supported cobalt(II) hydride (DUT-5-CoH) is a versatile solid catalyst for chemoselective hydrogenation of a range of nonpolar and polar arenes, including heteroarenes such as pyridines, quinolines, isoquinolines, indoles, and furans to afford cycloalkanes and saturated heterocycles in excellent yields. DUT-5-CoH exhibited excellent functional group tolerance and could be reusable at least five times without decreased activity. The same MOF-Co catalyst was also efficient for tandem hydrogenation–hydrodeoxygenation of aryl carbonyl compounds, including biomass-derived platform molecules such as furfural and hydroxymethylfurfural to cycloalkanes. In the case of hydrogenation of cumene, our spectroscopic, kinetic, and density functional theory (DFT) studies suggest the insertion of a trisubstituted alkene intermediate into the Co–H bond occurring in the turnover limiting step. Our work highlights the potential of MOF-supported single-site base–metal catalysts for sustainable and environment-friendly industrial production of chemicals and biofuels.

Novel hexahydrospiro[piperidine-4,1′-pyrrolo[3,4-c]pyrroles: Highly selective small-molecule nociceptin/orphanin FQ receptor agonists

Novel hexahydrospiro[piperidine-4,1′-pyrrolo[3,4-c]pyrroles that act as potent and selective orphanin FQ/nociceptin (N/OFQ) receptor (NOP) agonists were identified. The best compound, (+)-5a, potently inhibited 3H-N/OFQ binding to the NOP recep

High potency sweetening agents

Substituted guanidines containing a tetrazole moiety are provided as high potency sweetening agents.