186501-24-6

Basic information

• Product Name: Methyl 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylate
• Synonyms: Methyl 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylate
• CAS NO: 186501-24-6
• Molecular Weight: 359.381
• Mol File: 186501-24-6.mol

Chemical Properties

• CAS DataBase Reference: Methyl 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylate(186501-24-6)
• EPA Substance Registry System: Methyl 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylate(186501-24-6)

Safety Data

• Hazardous Substances Data: 186501-24-6(Hazardous Substances Data)

Upstream product

• 17672-21-8 2-amino-3-hydroxy-benzoic acid methyl ester 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 
• 548-93-6 3-hydroxyanthranilic acid 
• 119-36-8 methyl salicylate 
• 69-72-7 salicylic acid 
• 55142-16-0 methyl 2-(benzyloxy)benzoate 
• 14389-86-7 2-benzyloxybenzoic acid 
• 186501-21-3 2-(2-(benzyloxy)benzoylamino)-3-hydroxybenzoic acid methyl ester 

Downstream Products

• 906095-21-4 2-(2-hydroxyphenyl)benzo[d]oxazole-4-carboxylic acid 
• 530112-67-5 2-[2-(benzyloxy)phenyl]-1H-benzimidazole-4-carboxylic acid 
• 530112-63-1 methyl 2-amino-3-{[2-(2-benzyloxyphenyl)-1,3-benzoxazol-4-yl]carbonyl}aminobenzoate 
• 729589-48-4 2-(2-benzyloxy-phenyl)-benzooxazole-4-carboxylic acid (2-hydroxy-phenyl)-amide 
• 186501-26-8 methyl 3-hydroxy-2-{[2-(benzyloxyphenyl)-1,3-benzoxazol-4-yl]carbonyl}aminobenzoate 
• 151271-53-3 2'-(2-hydroxyphenyl)-2,4'-bibenzoxazole-4-carboxylic acid methyl ester 
• 153373-42-3 2-(2-Benzyloxy-phenyl)-benzooxazole-4-carbonyl chloride 
• 186501-25-7 2-(2-(benzyloxy)phenyl)benzo[d]oxazole-4-carboxylic acid 

Relevant articles and documents

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Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles

Four classes of UK-1 analogues were synthesized and their cytotoxicity testing against human A-549, BFTC-905, RD, MES-SA, and HeLa carcinoma cell lines was determined. The results revealed that UK-1 and four of these analogues (15-18) are potent against the cancer cell lines. In particular, compound 16 is more potent than UK-1 against A-549 and HeLa cell lines, and compounds 15, 17, and 18 selectively exhibit potent cytotoxic activity against the BFTV-905 cells (IC50 9.6 μM), A-549 cells (IC50 6.6 μM), and MES-SA cells (IC50 9.2 μM), respectively.

UK-1 analogues: methods of preparation and use

The present invention includes a number of structural analogues of UK-1. A comparision of the anticancer activity of the UK-1 analogues with their ability to inhibit the growth of methicillin-sensitive and methicillin-resistant Staphylococcus aureus demon

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