906095-21-4Relevant academic research and scientific papers
Synthetic method of anticancer drug UK-1
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, (2018/03/26)
The invention discloses a synthetic method of an anticancer drug UK-1. The method comprises the following steps: mixing a methyl 2-amino-3-hydroxybenzoate compound, an aldehyde and a molecular sieve to generate a mixture; performing heating reflux on the
Synthesis of caboxamycin and its derivatives using eco-friendly oxidation
Tagawa, Yoshinobu,Koba, Hiroki,Tomoike, Kazuhiro,Sumoto, Kunihiro
, p. 867 - 874 (2011/05/17)
The reaction of 3-hydroxyanthranilic acid or methyl 3-hydroxyanthranilate with O-benzylsalicylaldehyde in xylenes gave benzoxazole derivatives, which lead to a novel benzoxazole antibiotic, caboxamycin via debenzylation or demethylation in good yield, in
Benzoxazole carboxamides for treating CINV and IBS-D
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Page/Page column 17, (2008/06/13)
Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.
