1871-89-2

Usage

Uses

Used in Organic Synthesis:
N,N'-Bis(2-hydroxyethyl)oxamide is used as a key intermediate for the synthesis of various organic compounds. Its unique structure allows it to participate in a range of reactions, such as condensation, substitution, and rearrangement, leading to the formation of diverse chemical products.
Used in Pharmaceuticals:
In the pharmaceutical industry, N,N'-Bis(2-hydroxyethyl)oxamide is utilized as a building block for the development of new drugs. Its ability to form hydrogen bonds and interact with other functional groups makes it a valuable component in the design of pharmaceutical molecules with specific biological activities.
Used in Agrochemicals:
N,N'-Bis(2-hydroxyethyl)oxamide is employed as a starting material in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the creation of compounds that can effectively target and control pests and weeds in agricultural settings.
Used in Dyestuff:
In the dyestuff industry, N,N'-Bis(2-hydroxyethyl)oxamide is used as a raw material for the synthesis of various dyes and pigments. Its reactivity and compatibility with other chemical components facilitate the development of colorants with desired properties, such as color intensity, stability, and solubility.

InChI:InChI=1/C6H12N2O4/c9-3-1-7-5(11)6(12)8-2-4-10/h9-10H,1-4H2,(H,7,11)(H,8,12)

Upstream product

• 2050-60-4 di-n-butyl oxalate 
• 141-43-5 ethanolamine 
• 95-92-1 oxalic acid diethyl ester 
• 120-86-5 N,N'-bis(2-hydroxyethyl)dithiooxamide 
• 553-90-2 Dimethyl oxalate 
• 471-46-5 Oxalamide 
• 816-27-3 ethyl 2-ethoxy-2-iminoacetate 
• 148705-17-3 diisopropenyl oxalate 
• 540-51-2 2-bromoethanol 
• 40227-15-4 N,N'-diacetyl-oxalamide 

Downstream Products

• 16813-43-7 N,N'-bis-(2-chloro-ethyl)-oxalamide 
• 98485-17-7 N,N'-bis(2-nitrooxyethyl)oxalamide 
• 62209-60-3 N,N'-bis(2-nitrooxyethyl)-N,N'-dinitrooxalamide 
• 14484-06-1 N-(2-hydroxyethyl)-1H-benzimidazole-2-carboxamide 
• 36697-72-0 4,4′,5,5′-Tetrahydro-2,2′-bioxazole 
• 40651-66-9 C₆H₈Cl₂N₄O₄ 

Relevant academic research and scientific papers

5T2 1A1 AND 6A1 2T2 SPIN TRANSITIONS IN IRON(II) AND IRON(III) COMPLEXES OF 2,2'-BI-2-IMIDAZOLINE AND RELATED LIGANDS

A series of six-co-ordinate iron(II) complexes IIL3>X2 (X =ClO4 or BPh4) of the bidentate ligands 2,2'-bi-2-imidazoline (L3), 2,2'-bi-1,4,5,6-tetrahyropyrimidine (L4), 2,2'-bi-2-oxazoline (L5), and 5,5'-dimethyl-2,2'-bi-2-oxazoline (L6) have been prepared and characterised by their physical properties.In all cases co-ordination is via the α-di-imine group.Magnetic susceptibility and Moessbauer effect measurements as a function of temperature show that the complexes of L5 and L6 are fully high-spin (S = 2) over the temperature range 90-360 K, while for complexes of L3 (X = ClO4 but not BPh4) and L4 (X = ClO4 and BPh4) a 5T2 1A1 spin transition is observed in this temperature range.Electronic spectra of the corresponding nickel(II) complexes indicate a correlation between Dq(Ni) and the spin ground state of the iron(II) complexes.The iron(III) complex IIIL33>3 is high-spin (S=5/2), while 43>3 has a 2T2 ground state but with a thermally accessible 6A1 excited state.Iron(III) complexes of L5 and L6 are unstable and could not be isolated.Reaction of the iron(II) complexes of L3 and L4 with dioxygen gave the iron(III) complexes IIIL2(L-H)>2 in good yield which may be reversibly converted to the IIIL3>(3+) species on treatment with one equvivalent og HClO4.The temperature-dependent magnetic moments of the complexes 2(L-H)>2 are interpreted in terms of 2T2 6A1 spin equlibria.

β-oxalylamino-substituted O-ethyl N-arylcarbamates and N-ethyl-N′-arylureas encapsulated into micelles of vinylimidazole–vinylcaprolactam copolymer

Low-molecular-weight compounds—β-oxalylamino-substituted O-ethyl carbamates and unsymmetrical ureas showing biological activity—have been synthesized and encapsulated into micelles of vinylimidazole–vinylcaprolactam copolymers. Solubilization in micelles has provided a preparation of water-soluble colloidal formulation of these compounds suitable for practical application.

A synthesis method of grass amide derivatives (by machine translation)

The present invention provides a D. amide derivatives of synthetic method. It adopts the D. amide and halogenated compound reaction, adding alkali, bidentate ligand, copper salt catalyst, solvent, the solvent reflux temperature of the reaction a certain period of time and then after treatment. The turf amide with a halo compound in a molar ratio of 1: 0.4 - 3.5; the turf amide with alkali molar ratio of 1: 1.0 - 3.0; the D. amide with the bidentate ligand molar ratio of 1:5 - 25 μM %; the turf amide with the molar ratio of the copper salt catalyst: 1:5 - 30 μM %. The process method is different from the reported oxalic acid diester or oxalyl with different amino substituted compound of method. The invention in the existing technology based on the use of a readily available and inexpensive D. as raw materials, accord with the green chemistry, to avoid colorless fuming liquid of the adding of the oxalyl, increase operability, is suitable for industrial production. (by machine translation)

Reactivity of β-amino alcohols against dialkyl oxalate: Synthesis and mechanism study in the formation of substituted oxalamide and/or morpholine-2,3-dione derivatives

The reactivity of various β-amino alcohols with dialkyl oxalates, in several reaction conditions, has been investigated. Linear disubstituted oxalamides were obtained with primary β-amino alcohols and linear tetrasubstituted oxalamides, or a mixture of linear tetrasubstituted oxalamides and cyclic morpholine-2,3-diones were obtained with N-substituted β-amino alcohols. A DFT study of the possible mechanism has been made. The theoretical results indicate that these reactions are not kinetically controlled, there is an equilibrium between all species and therefore follow a thermodynamic control. The different behavior between the primary β-amino alcohols and N-methyl β-amino alcohols is due to the greater stability of linear disubstituted oxalamides with respect to linear tetrasubstituted oxalamides. The energy of tetrasubstituted oxalamides is closer to the energy of the corresponding morpholine-2,3-diones.

Use of particular polyols for preventing the hair from breaking, composition comprising them and cosmetic hair treatment process

The present invention relates to the use of polyols of formula (I): or a salt thereof, for preventing the hair from breaking. The invention also relates to a cosmetic composition comprising at least one such polyol or a salt thereof, in a cosmetically acceptable medium, and also to a cosmetic hair treatment process using the said composition.

Method for the synthesis of amides and related products from esters or ester-like compounds

A versatile, eco-friendly, and efficient method for the convenient conversion of esters and ester-like compounds into amides, peptides, carbamates, ureas, oxamides, oxamates, hydrazides, oxazolidinones, pyrazolones, oxazolidinediones, barbituric acids, and other molecules containing one or more OCN moieties in the presence of a diol or polyol is disclosed.

Piperidyl organosiloxanes and polymer substrates light-stabilized therewith

Novel piperidyl organosiloxanes, well adapted for the light/UV-stabilization of a wide variety of polymer substrates, e.g., polyolefins and polyalkadienes, have the structural formula (I): STR1

N-acyl derivatives of aminoalcohols with polycarboxylic acids able to modulate mast cells in inflammatory processes having neuroimmunogenic origin

N-acyl derivatives of aminoalcohols with bicarboxylic or tricarboxylic acids able to modulate the degranulation process consequent to the mast cells activation in inflammatory processes caused by supramaximal stimuli of neurogenic and immunogenic origin.

Novel acyclic ligands. Part 1. Synthesis of some dicarboxamide derivatives

The synthesis of three novel acyclic bis(amino-substituted amides), 3, 4 and 5, each of which possesses a bridging carbon atom carrying a suitable amino-bearing functionality, is described. These compounds may serve as contrast agents in magnetic resonance imaging.

Use of N-acyl derivatives of aminoalcohols with polycarboxylic acids for the manufacture of a medicament for the treatment of pathologies relating to mast cells

N-acyl derivatives of aminoalcohols with polycarboxylic acids able to modulate the degranulation process consequent to the mast cells activation in inflammatory processes caused by overmaximal stimuli of neurogenic and immunogenic origin.