187222-18-0

Basic information

• Product Name: Methyl 4-Methoxy-3,5-diMethylpicolinate
• Synonyms: Methyl 4-Methoxy-3,5-diMethylpicolinate;methyl 4-methoxy-3,5-dimethylpyridine-2-carboxylate
• CAS NO: 187222-18-0
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.21512
• Mol File: 187222-18-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 4-Methoxy-3,5-diMethylpicolinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-Methoxy-3,5-diMethylpicolinate(187222-18-0)
• EPA Substance Registry System: Methyl 4-Methoxy-3,5-diMethylpicolinate(187222-18-0)

Safety Data

• Hazardous Substances Data: 187222-18-0(Hazardous Substances Data)

Usage

General Description

Methyl 4-Methoxy-3,5-dimethylpicolinate is a chemical compound with the molecular formula C12H15NO3. It is a derivative of picolinic acid and is commonly used in the pharmaceutical industry for its potential therapeutic applications. Methyl 4-Methoxy-3,5-diMethylpicolinate has a methoxy group and two methyl groups attached to the picolinate ring, which gives it unique chemical properties. It is often used as a building block in the synthesis of other organic compounds and has potential use as a drug intermediate. Additionally, its unique chemical structure may contribute to its potential biological activity and pharmaceutical uses.

Upstream product

• 67-56-1 methanol 
• 187222-17-9 4-Chloro-2-ethoxycarbonyl-3,5-Lutidine 
• 447461-21-4 2-carboxy-4-hydroxy-3,5-lutidine 
• 187222-15-7 N-benzyl-2-ethoxycarbonyl-3,5-dimethyl-4-pyridone 
• 187222-16-8 2-Ethoxycarbonyl-3,5-dimethyl-4(1H)-pyridone 
• 187222-13-5 3,5-Dimethyl-2-ethoxycarbonyl-4-pyrone 
• 187222-12-4 3,5-dimethyl-4-oxo-4H-pyran-2-carboxylic acid 
• 187222-11-3 1-ethoxy-2-methylpent-1-en-3-one 
• 50421-81-3 1-hydroxy-2-methyl-1-penten-3-one 

Downstream Products

• 86604-78-6 (4-methoxy-3,5-dimethylpyridin-2-yl)methanol 

Relevant articles and documents

Synthesis of pharmaceutically useful pyridine derivatives

A process is provided for the preparation of compounds of formula I, useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R1=H or CH3, R2=H or CH3, R3=Alkoxy (1-4C), OCH2CF3, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula I employs a free radical reaction to functionalize the 2-position.

Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine

A process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine including the steps of acylating 2-methyl-1-penten-1-alkoxy-3-one to obtain 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone; ammonolyzing 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone to obtain 2-alkoxycarbonyl-3,5-dimethyl-4(1H)-pyridone; halogenating 2-alkoxycarbonyl-3,5-dimethyl-4(1H)-pyridone to obtain 2-alkoxycarbonyl-4-halo-3,5-dimethylpyridine; methoxylating 2-alkoxycarbonyl-4-halo-3,5-dimethylpyridine to obtain 2-methoxycarbonyl-3,5-dimethyl-4-methoxypyridine; and reducing 2-methoxycarbonyl-3,5-dimethyl-4-methoxypyridine to obtain 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine.