18762-60-2Relevant academic research and scientific papers
Titanium and Cobalt Bimetallic Radical Redox Relay for the Isomerization of N -Bz Aziridines to Allylic Amides
Wood, Devin P.,Guan, Weiyang,Lin, Song
supporting information, p. 4213 - 4220 (2021/08/10)
Herein a bimetallic radical redox-relay strategy is employed to generate alkyl radicals under mild conditions with titanium(III) catalysis and terminated via hydrogen atom transfer with cobalt(II) catalysis to enact base-free isomerizations of N-Bz aziridines to N-Bz allylic amides. This reaction provides an alternative strategy for the synthesis of allylic amides from alkenes via a three-step sequence to accomplish a formal transpositional allylic amination.
Synthesis of N-acylaziridines from β-amido selenides
Ward,Cooper,Ward
, p. 944 - 945 (2007/10/03)
The low temperature oxidation of β-amido selenides with MCPBA affords the corresponding β-amido selenones. In situ treatment of the selenones with KOtBu gives N-acylaziridines in good to excellent yield.
The synthesis of N-benzoyl aziridines from β-benzamidoalkyl phenyl selenides
Ward, Virginia R.,Cooper, Matthew A.,Ward, A. David
, p. 195 - 201 (2007/10/03)
β-Benzamidoalkyl phenyl selenides can be oxidised, using mCPBA, to the corresponding selenones which can be cyclised to oxazolines or aziridines depending on the reaction conditions. In neutral or weakly basic conditions the oxazoline is the major product
Asymmetric Catalysis by Vitamin B12: The Isomerization of Achiral Aziridines to Optically Active Allylic Amines
Zhang, Zhong da,Scheffold, Rolf
, p. 2602 - 2615 (2007/10/02)
Achiral N-acylaziridines are isomerized to optically active N-acyl-allylamines in ee's of up to 95percent by catalytic amounts of cob(I)alamin in MeOH.
