187657-92-7

Basic information

• Product Name: 1-(1-BENZOFURAN-3-YL)-2-BROMO-1-ETHANONE
• Synonyms: 1-(1-BENZOFURAN-3-YL)-2-BROMO-1-ETHANONE;1-(Benzofuran-3-yl)-2-bromoethan-1-one;2,4-Bis(methylsulfonyl)phenylhydrazine;(1-Benzofuran-3-yl)-2-bromo-1-ethanone;1-(1-benzofuran-3-yl)-2-broMoethan-1-one;1-(Benzofuran-3-yl)-2-broMoethanone
• CAS NO: 187657-92-7
• Molecular Formula: C₁₀H₇BrO₂
• Molecular Weight: 239.07
• EINECS: 260-718-7
• Product Categories: Furan&Benzofuran
• Mol File: 187657-92-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 136 °C
• Boiling Point: 306.782 °C at 760 mmHg
• Flash Point: 139.337 °C
• Appearance: white to light yellow crystal powder
• Density: 1.583 g/cm³
• Vapor Pressure: 0.000755mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 1-(1-BENZOFURAN-3-YL)-2-BROMO-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-BENZOFURAN-3-YL)-2-BROMO-1-ETHANONE(187657-92-7)
• EPA Substance Registry System: 1-(1-BENZOFURAN-3-YL)-2-BROMO-1-ETHANONE(187657-92-7)

Safety Data

• Hazard Codes: C,Xi
• Statements: 36/37/38-34
• Safety Statements: 26-36/37/39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 187657-92-7(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

InChI:InChI=1/C10H7BrO2/c11-5-9(12)8-6-13-10-4-2-1-3-7(8)10/h1-4,6H,5H2

Upstream product

• 66611-15-2 3-acetylbenzo[b]furan 
• 7789-45-9 copper(II)bromide 

Downstream Products

• 66611-15-2 3-acetylbenzo[b]furan 
• 1300731-09-2 1-(benzofuran-3-yl)-2-(2-(1-trityl-1H-imidazol-4-yl)phenoxy)ethanone 
• 1300728-62-4 4-(2-(2-(benzofuran-3-yl)propoxy)phenyl)-1H-imidazole 
• 1300731-10-5 C₃₉H₃₀N₂O₂ 
• 1300728-61-3 4-(2-((2-(benzofuran-3-yl)allyl)oxy)phenyl)-1H-imidazole 
• 877263-54-2 C₁₈H₁₇NO₂ 
• 233671-42-6 4-acetylamino-3-(2'-oxo-2'-<3''-benzofuryl>-ethyl)-aminobenzoic acid t-butyl ester 
• 1187820-53-6 [3-[2-(Benzofuran-3-yl)imidazo[1,2-a]pyridin-6-yl]phenyl]methanol 
• 343614-12-0 (S)-(+)-(benzofuran-3-yl)oxirane 

Relevant articles and documents

Baker's yeast-mediated synthesis of (R)- and (S)-heteroaryl-ethane-1,2-diols

Baker's yeast-mediated enantioselective bioreduction of 1-(heteroaryl)-2-hydroxyethanones and 2-acetoxy-1-(hetero-aryl)ethanones was used for the enantioselective synthesis of both (R)- and (S)-benzofuranyl-, benzo[b]thiophenyl- and benzo[d]thiazolyl-ethane-1,2-diols.

Enantioselective synthesis of 2- and 3-benzofuryl β-amino alcohols

Enantioselective reduction of 2- and 3-bromoacetylbenzofurans with (-)-B-chlorodiisopinocampheylborane produced the corresponding bromohydrins which were transformed into (S)-(benzofuran-2-yl)oxirane of 70% ee and (S)-(benzofuran-3-yl)oxirane of 71% ee, respectively. The epoxides treated with primary alkylamines gave the corresponding (S)-1-(benzofuran-2- and -3-yl)-2-(alkylamino) ethanols.