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Carboxyamidotriazole orotate is a synthetic chemical compound derived from orotic acid, a naturally occurring substance in the body that plays a crucial role in the synthesis of pyrimidines, which are vital components of DNA and RNA. CARBOXYAMIDOTRIAZOLE OROTATE has garnered attention in the field of cancer research and therapy due to its potential anti-cancer properties. It is believed to exert its effects by inhibiting the growth and spread of tumor cells through the disruption of various signaling pathways that are integral to cancer development and progression. Furthermore, carboxyamidotriazole orotate has demonstrated antioxidant and anti-inflammatory capabilities, which may enhance its therapeutic potential in the treatment of cancer and other diseases. Ongoing research is focused on elucidating the mechanisms of action and the full extent of its effects, with the goal of establishing carboxyamidotriazole orotate as a novel anti-cancer agent.

187739-60-2

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187739-60-2 Usage

Uses

Used in Cancer Research and Therapy:
Carboxyamidotriazole orotate is utilized as a potential anti-cancer agent for its ability to inhibit the growth and spread of tumor cells. It targets and disrupts key signaling pathways involved in cancer development and progression, thereby offering a novel approach to cancer treatment.
Used in Antioxidant and Anti-inflammatory Applications:
Beyond its anti-cancer properties, carboxyamidotriazole orotate is also recognized for its antioxidant and anti-inflammatory effects. These additional therapeutic benefits may contribute to its overall utility in the treatment of cancer and other diseases where oxidative stress and inflammation play a significant role.
Used in Pharmaceutical Development:
As a compound with demonstrated potential in cancer treatment, carboxyamidotriazole orotate is employed in the development of new pharmaceuticals. Researchers are investigating its mechanisms of action and potential synergistic effects with existing treatments to enhance its therapeutic efficacy and safety profile.
Used in Preclinical and Clinical Studies:
Carboxyamidotriazole orotate is a subject of preclinical and clinical studies aimed at understanding its full potential as an anti-cancer agent. These studies are crucial for determining the appropriate dosages, administration methods, and potential side effects, as well as for establishing its efficacy in various types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 187739-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,7,3 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 187739-60:
(8*1)+(7*8)+(6*7)+(5*7)+(4*3)+(3*9)+(2*6)+(1*0)=192
192 % 10 = 2
So 187739-60-2 is a valid CAS Registry Number.

187739-60-2Downstream Products

187739-60-2Relevant academic research and scientific papers

Novel compositions and processes for preparing 5-amino or substituted amino 1,2,3-triazoles and triazoles orotate formulations

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, (2014/07/23)

New polymorphs of 5-amino or substituted amino 1,2,3-triazole and substituted derivatives thereof, of orotates of the carboxyamidotriazoles, of formulations of the triazoles and orotic acid in the ratio of 1:1 to 1:4 (base:acid) and of safer processes of

NOVEL COMPOSITIONS AND PROCESSES FOR PREPARING 5-AMINO OR SUBSTITUTED AMINO 1,2,3-TRIAZOLES AND TRIAZOLE OROTATE FORMULATIONS

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, (2011/04/14)

New polymorphs of 5-amino or substituted amino 1, 2, 3-triazole and substituted derivatives thereof, of orotates of the carboxyamidotriazoles, of formulations of the triazoles and orotic acid in the ratio of 1:1 to 1:4 (base:acid) and of safer processes o

Method of increasing drug oral bioavailability and compositions of less toxic orotate salts

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Page/Page column 6, (2008/06/13)

The present invention relates generally to the method of increasing the oral bioavailability, reducing chemotherapy induced toxicity and side effects, and improving the effectiveness of pharmaceutical agents that are poorly absorbed from the gastrointesti

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