187807-24-5

Upstream product

• 142009-99-2 4-(benzylamino)cyclohexane-1-one 
• 188562-93-8 4-[N-benzyl-N-(tert-butoxycarbonyl)amino]cyclohex-1-en-yl trifluoromethanesulfonate 
• 188562-91-6 tert-butyl N-benzyl(4-oxocyclohexyl)carbamate 
• 187807-23-4 N-benzyl-N-(3-cyclohexenyl)amine 
• 422507-52-6 4-[N-benzyl-N-(tert-butoxycarbonyl)amino]cyclohexan-1-one p-toluensulfonylhydrazone 
• 67132-62-1 dimethyl aluminum selenide 
• 422507-12-8 4-[N-benzyl-N-(methoxycarbonylmethyl)amino]-1-cyclohexene 
• 422507-07-1 trans-4-[N-benzyl-N-(tert-butoxycarbonyl)amino]cyclohexan-1-ol 
• 422507-09-3 4-[N-benzyl-N-(tert-butoxycarbonyl)amino]cyclohex-1-ene 

Relevant academic research and scientific papers

Decarbonylative radical cyclization of α-amino selenoesters upon electrophilic alkenes. A general method for the 6-azabicyclo[3.2.1]octane synthesis

α-Amino selenoester-tethered electronically poor alkenes on treatment with tributyltin hydride or TTMSS undergo intramolecular radical cyclization to provide 6-azabicyclo[3.2.1]octanes through 1-aminomethyl radical intermediates.

A New Method to Generate α-Aminoalkyl Radicals: Treatment of Methyl α-Amino Selenoesters with Hydride Reagents. Synthesis of 6-Azabicyclo[3.2.1]octanes by Radical Cyclization

A new method to generate α-aminoalkyl radicals and its application to the synthesis of 6-azabicyclo[3.2.1]octanes is described. α-Amino selenoesters on heating with Bu3SnH or (Me3Si)3SiH undergo decarbonylation of the initially formed acyl radical to give the corresponding α-amino radical which could be trapped intramolecularly with a double bond bearing an electron-withdrawing group.