422507-09-3Relevant academic research and scientific papers
Chlorine atom transfer radical 6-exo cyclizations of carbamoyldichloroacetate-tethered alkenes, enol acetates and α,β-unsaturated nitriles leading to morphans
Diaba, Faiza,Martinez-Laporta, Agustin,Bonjoch, Josep
, p. 2371 - 2378 (2014/04/17)
The CuI-mediated atom transfer radical cyclization of amino-tethered dichloromalonamides and electron-rich, electron-poor, and nonactivated double bonds is a useful methodology for the synthesis of 2-azabicyclo[3.3.1]nonanes. A study of the rea
A simple and efficient synthesis of N-substituted cyclohex-3-enamines
Alvarez-Perez, Monica,Marco-Contelles, Jose
experimental part, p. 3649 - 3653 (2010/04/05)
A straightforward preparation of N-substituted cyclohex-3-enamines starting from the commercially available trans-4-aminocyclohexanol hydrochloride is described. Cyclohex-3-enamino-functionalized compounds have proven to be interesting intermediates in me
N-Arylmethyl-7-azabicyclo[2.2.1]heptane derivatives: synthesis and reaction mechanisms
Gómez, Elena,Marco-Contelles, José,Soriano, Elena,Jimeno, María L.
experimental part, p. 9224 - 9232 (2010/01/06)
N-Arylmethyl-7-azabicyclo[2.2.1]heptane (I) derivatives have been synthesized by deprotection of N-protected, N-(arylmethyl)cyclohex-3-enamines, bromination of the resulting secondary cyclohex-3-enamines,?followed by base-promoted cyclization (route a), o
Decarbonylative radical cyclization of α-amino selenoesters upon electrophilic alkenes. A general method for the 6-azabicyclo[3.2.1]octane synthesis
Quirante, Josefina,Vila, Xavier,Escolano, Carmen,Bonjoch, Josep
, p. 2323 - 2328 (2007/10/03)
α-Amino selenoester-tethered electronically poor alkenes on treatment with tributyltin hydride or TTMSS undergo intramolecular radical cyclization to provide 6-azabicyclo[3.2.1]octanes through 1-aminomethyl radical intermediates.
