187848-83-5Relevant academic research and scientific papers
Iron(II) and zinc(II) complexes with designed pybox ligand for asymmetric aqueous Mukaiyama-aldol reactions
Jankowska, Joanna,Paradowska, Joanna,Rakiel, Bartosz,Mlynarski, Jacek
, p. 2228 - 2231 (2007/10/03)
An iron(II) complex with a hindered hydroxyethyl-pybox (he-pybox) ligand shows improved catalytic activity and enantioselectivity for asymmetric Mukaiyama-aldol reactions in aqueous media. This water-stable chiral Lewis acid promotes condensation of aroma
Asymmetric mukaiyama-aldol reaction in aqueous media promoted by zinc-based chiral lewis acids
Mlynarski, Jacek,Jankowska, Joanna
, p. 521 - 525 (2007/10/03)
Asymmetric aldol reactions in aqueous media have been realized by using zinc-based chiral Lewis acids. The aldol products have been obtained with high yield, diastereocontrol and a good level of enantioselectivity. The reactivity of both acetophenone and
Lewis base-promoted aldol reaction of dimethylsilyl enolates in aqueous dimethylformamide: Use of calcium chloride as a Lewis base catalyst
Miura, Katsukiyo,Nakagawa, Takahiro,Hosomi, Akira
, p. 536 - 537 (2007/10/03)
In the presence of CaCl2, dimethylsilyl (DMS) enolates smoothly reacted with aldehydes under mild conditions to give aldol adducts in good to high yields. The catalytic activities of various metal and tetrabutylammonium salts have revealed that CaCl2 works as a Lewis base catalyst to activate DMS enolates. The CaCl2-promoted reaction proceeded even in the presence of water or in pure water. This catalytic system was applicable to the aldol reaction with aqueous aldehydes such as formalin. Copyright
