18791-02-1

Basic information

• Product Name: 2,3-Dibromopropionyl chloride
• Synonyms: 2,3-DIBROMOPROPIONYL CHLORIDE;2,3-dibromopropanoylchloride;2,3-dibromo-propionylchlorid;alpha,beta-dibromopropionylchloride;2.3-Dibromoproionyl chloride;2.3-DIBROMOPROPIONY1[I1] CHLORIDE;2,3-dibromo-propanoyl chlorid;2,3-Dibromopropanoic acid chloride
• CAS NO: 18791-02-1
• Molecular Formula: C₃H₃Br₂ClO
• Molecular Weight: 250.32
• EINECS: 242-575-2
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 18791-02-1.mol

Chemical Properties

• Boiling Point: 191-193 °C(lit.)
• Flash Point: 152 °F
• Appearance: Clear colorless to yellow/Liquid
• Density: 2.181 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.5mmHg at 25°C
• Refractive Index: n20/D 1.542(lit.)
• Sensitive: Moisture Sensitive
• BRN: 1749801
• CAS DataBase Reference: 2,3-Dibromopropionyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dibromopropionyl chloride(18791-02-1)
• EPA Substance Registry System: 2,3-Dibromopropionyl chloride(18791-02-1)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37
• Safety Statements: 23-26-27-28-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• RTECS: UG6657500
• F: 19-21
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 18791-02-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dibromopropionyl chloride is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its application is particularly relevant in the synthesis of complex organic molecules with potential therapeutic properties.
Used in Synthesis of Acromelic Acid A:
2,3-Dibromopropionyl chloride is used as a key intermediate in the synthesis of acromelic acid A, a compound with potential biological activities. The bromine atoms in the molecule facilitate the formation of the desired product through a series of chemical reactions.
Used in Synthesis of 2,3-Diaminopropionanilides:
2,3-Dibromopropionyl chloride is used as a starting material in the synthesis of 2,3-diaminopropionanilides, which are important compounds in the development of new pharmaceuticals. The bromine atoms in the molecule allow for the introduction of the amino and aniline groups, leading to the formation of the target compound.
Used in Synthesis of 1,4-Dideoxy-1,4-Iminolyxitol and 1,4-Dideoxy-1,4-Iminoribitol:
2,3-Dibromopropionyl chloride is used as a synthetic building block in the preparation of 1,4-dideoxy-1,4-iminolyxitol and 1,4-dideoxy-1,4-iminoribitol. These compounds are of interest in the field of carbohydrate chemistry and have potential applications in the development of new drugs and pharmaceuticals.

InChI:InChI=1/C3H3Br2ClO/c4-1-2(5)3(6)7/h2H,1H2/t2-/m0/s1

Upstream product

• 600-05-5 2,3-dibromopropionic acid 
• 814-68-6 acryloyl chloride 

Downstream Products

• 90326-66-2 2,3-dibromo-propionic acid anilide 
• 51246-69-6 2,3-dibromo-propionic acid-(2,6-dimethyl-anilide) 
• 397849-96-6 L-(-)-Menthyl-2,3-dibrom-propionat 
• 90841-79-5 2,3-dibromo-N-methyl-N-phenylpropanamide 
• 83507-22-6 2-[(Z)-Benzylimino]-3-methyl-4-methylene-thiazolidin-5-one 
• 78406-69-6 2,3-Dibromo-N-(2-butoxy-phenyl)-propionamide 
• 78414-53-6 2,3-Dibromo-N-(3,4-diethoxy-phenyl)-propionamide 
• 123528-59-6 2-α,β-dibromoethyl-4-perfluorohexyl-6-phenyl-s-triazine 
• 111773-30-9 N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2-bromo-2-propenoic acid ami 
• 111773-29-6 N-<3-(tert-butoxycarbonyl)-6-methylphenyl>-2,2-dibromopropanoic acid amide 
• 78406-66-3 2,3-Dibromo-N-(3-methoxy-phenyl)-propionamide 
• 78406-65-2 2,3-Dibromo-N-(2-methoxy-phenyl)-propionamide 
• 143833-47-0 (S)-1-((S)-1-Phenyl-ethyl)-aziridine-2-carboxylic acid 4-methoxy-phenyl ester 
• 143833-48-1 (R)-1-((S)-1-Phenyl-ethyl)-aziridine-2-carboxylic acid 4-methoxy-phenyl ester 

Relevant articles and documents

A 2, 3 - two bromine propionyl chlorides production process (by machine translation)

The present invention relates to the field of producing chemical products, especially 2, 3 - two bromine propionyl chlorides production field. 2. 3 - two bromine propionyl chlorides is an important chemical raw materials. Currently in production have different production process. The process flow includes: 1, addition; 2, distillation. (by machine translation)

METHOD OF INCREASING THE SPF RATING AND COMPOUNDS SUITABLE FOR INCREASING THE SPF RATING OF FIBRE OR FABRIC

PCT No. PCT/AU93/00412 Sec. 371 Date Jun. 15, 1995 Sec. 102(e) Date Jun. 15, 1995 PCT Filed Aug. 12, 1993 PCT Pub. No. WO94/04515 PCT Pub. Date Mar. 3, 1994The present invention provides a method of increasing the sun protection factor (SPF) rating of a fiber or fabric, comprising the steps of providing a UVR absorber, applying the UVR absorber to a fabric, whereby the UVR absorber is attached to the fiber and an application of less than 3% UVR absorber on weight of fiber produces an SPF rating of greater than 20 for the UVR absorber and fabric combination.

Process for the preparation of 2,3-dibromopropionyl chloride

An improved process for the preparation of 2,3-dibromopropionyl chloride, which comprises brominating acrylic acid, adding iron powder or an iron salt to the resultant melt, chlorinating the dibromopropionic acid obtained, and removing the volatile components. The 2,3-dibromopropionyl chloride is obtained in high yield and purity and is an intermediate for synthesising in particular reactive dyes.

Reaction of (α-halogenoalkyl)thiiranes with nucleophilic reagents I. Reaction with morpholine

By means of deuterated compounds it was established that (chloromethyl)thiirane reacts with morpholine by a mechanism involving initial opening of the thiirane ring followed by recyclization.In the case of (bromomethyl)thiirane direct substitution of the bromine begins to compete with this mechanism. 2-Methyl-2-(chloromethyl)thiirane, 2,2-dimethyl-3-(chloromethyl)thiirane, and the diastereomeric (1-chloroethyl)thiiranes were synthesized, and their reactivity toward morpholine was studied.

Process for the preparation of fibre-reactive azo compounds containing a phenylenediamine diazo component

The invention relates to a process for the preparation of azo compounds of the formula STR1 wherein K is the radical of a coupling component, R is a water-solubilising group and X is a fibre-reactive radical, and the benzene ring A may be further substituted, which process comprises reacting a compound of the formula STR2 in an aqueous medium containing 5 to 25% by weight of an alkali metal halide or alkali metal sulfate, based on the weight of the medium, with a compound which introduces the radical X to give the compound of the formula STR3 diazotising said compound direct and coupling the diazotisation product with a coupling component of the formula in which formulae (2), (3) and (4) A, R, X and K are as defined for formula (1).