18797-94-9

Basic information

• Product Name: N-[(1E)-2-(4-methoxyphenyl)ethenyl]acetamide
• Synonyms: N-[(1E)-2-(4-methoxyphenyl)ethenyl]acetamide
• CAS NO: 18797-94-9
• Molecular Weight: 191.23
• Mol File: 18797-94-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-[(1E)-2-(4-methoxyphenyl)ethenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1E)-2-(4-methoxyphenyl)ethenyl]acetamide(18797-94-9)
• EPA Substance Registry System: N-[(1E)-2-(4-methoxyphenyl)ethenyl]acetamide(18797-94-9)

Safety Data

• Hazardous Substances Data: 18797-94-9(Hazardous Substances Data)

Upstream product

• 943-88-4 4-(p-methoxyphenyl)-3-butene-2-one 
• 108-24-7 acetic anhydride 
• 74447-44-2 1-azido-2-(4-methoxyphenyl)ethane 
• 60-35-5 acetamide 
• 6303-59-9 (Z)-1-bromo-2-(4-methoxyphenyl)ethene 
• 118653-07-9 [(Z)-2-(4-Methoxy-phenyl)-vinyl]-carbamic acid methyl ester 
• 118653-29-5 [(S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propionyl]-[(Z)-2-(4-methoxy-phenyl)-vinyl]-carbamic acid methyl ester 
• 5676-64-2 (Z)-3-(4-methoxyphenyl)acrylic acid 
• 115502-66-4 N-(4-methoxy-styryl)-acetamide 
• 118653-08-0 [(E)-2-(4-Methoxy-phenyl)-vinyl]-carbamic acid methyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 86069-36-5 4-(p-methoxyphenyl)-3-buten-2-one oxime 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 118653-19-3 Acetyl-[(E)-2-(4-methoxy-phenyl)-vinyl]-carbamic acid methyl ester 

Downstream Products

• 185244-97-7 2-chloro-5-(4-methoxyphenyl)-nicotinaldehyde 
• 556-02-5 tyrosine 

Relevant articles and documents

METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN

Provided is a method for preparing an enamide compound, which includes reacting an organic azide compound having α-hydrogen and an anhydride by addition of a ruthenium complex catalyst in the presence of an ionic liquid, and a ruthenium complex catalyst u

Regioselective Rh(I)-catalyzed sequential hydrosilylation toward the assembly of silicon-based peptidomimetic analogues

A highly regioselective Rh(I)-catalyzed hydrosilylation of enamides is presented. This mild protocol allows access to a wide variety of different arylsilanes with substitution at the β-position of the enamide and functionalization on the alkyl chain tethered to the silane. This protocol is extended to include a sequential one-pot hydrosilylation. Using diphenylsilane as the appendage point, hydrosilylation of a protected allyl alcohol followed by hydrosilylation of an enamide generates a complex organosilane in one step. This highly convergent strategy to synthesize these functionalized systems now provides a way for the rapid assembly of a diverse collection of silane-based peptidomimetic analogues.

Facile and selective synthesis of chloronicotinaldehydes by the Vilsmeier reaction

Eleven enamides were prepared by adopting different procedures. The various enamides prepared were subjected to Vilsmeier reaction using (i) POCl3/DMF; (ii) diphosgene/DMF; (iii) triphosgene/DMF leading to the formation of various multisubstituted chloronicotinaldehydes. Studies carried out indicate that Vilsmeier reagent concentration and the replacement of POCl3 by diphosgene or triphosgene, provides excellent selectivity and higher yields. Under modified reaction conditions one can get only chloronicotinaldehydes and not the chloropyridines as products. The various advantages in using diphosgene and triphosgene are illustrated. The mechanism of formation of chloronicotinaldehyde was discussed.