188255-40-5Relevant academic research and scientific papers
TBuO 2H/Cu(acac) 2-Mediated Intramolecular Oxidative Lactonization of o -Allyl Arylaldehydes: Synthesis of 1-Oxoisochromans
Chang, Meng-Yang,Lai, Kai-Xiang,Chen, Kuan-Ting
, p. 527 - 537 (2020/10/19)
A concise route for the tBuO 2H/Cu(acac) 2-mediated synthesis of 1-oxoisochromans is described. This includes: (i) oxidation of oxygenated o -allyl arylaldehydes and (ii) sequential intramolecular lactonization of the resulting olefin-containing benzoic acids. A plausible mechanism is proposed and discussed.
A novel method for the synthesis of substituted naphthalenes and phenanthrenes
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Amanda L.
, p. 787 - 797 (2007/10/03)
A new method for the synthesis of substituted naphthalenes and phenanthrenes was discussed. A formal synthesis of tanshinone I was also studied. Natural products that contain a naphthalene or phenanthrene nucleus often exhibit biological activity, which makes them attractive targets in organic synthesis. The results showed that the reaction can be proceed through at least two different pathways.
A novel synthesis subtituted naphthalenes
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Ainanda L.
, p. 893 - 896 (2007/10/03)
Irradiation of 2-allylated acylbenzenes in DMF in the presence of potassium tert-butoxice constitutes a novel synthesis of substituted naphthalenes, including arylnaphthalenes. Typical examples including the conversions (1) → (2), (8) → (11) and (15) → (16).
