267898-02-2Relevant academic research and scientific papers
Synthesis of 2-hydroxymethyl-2,3-dihydrobenzofurans
Chang, Meng-Yang,Lin, Shin-Ying,Chanp, Chieh-Kai
, p. 1905 - 1912 (2014/08/18)
A one-pot protocol toward 2-hydroxymethyl-2,3-dihydrobenzofurans (1) starting with oxygenated o-allylbenzaldehydes (3) was described. The facile one-pot process was carried out by the oxidation of o-allylbenzaldehydes (3) with Oxone in the co-solvent of acetone and DMF in the presence of aqueous EDTA solution and then intramolecular ring-closure of the resulting o-allylphenols (2) in acceptable yields.
Synthesis of substituted indenes from isovanillin via claisen rearrangement and ring-closing metathesis
Huang, Keng-Shiang,Wang, Eng-Chi
, p. 383 - 391 (2007/10/03)
A new synthesis of substituted indenes was studied. Based on Claisen rearrangement, Wittig reaction and ring-closing metathesis (RCM), a series of substituted indenes was synthesized from isovanillin in good yields.
Syntheses of substituted naphthalenes and naphthols
Huang, Keng-Shiang,Wang, Eng-Chi,Chen, Hsing-Ming
, p. 585 - 605 (2007/10/03)
Syntheses of substituted naphthalenes and naphthols are described. Based on Claisen rearrangement, ring-closing metathesis (RCM), and related reactions, isovanillin was successfully transformed into a series of substituted naphthalenes and naphthols with
A novel method for the synthesis of substituted naphthalenes and phenanthrenes
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Amanda L.
, p. 787 - 797 (2007/10/03)
A new method for the synthesis of substituted naphthalenes and phenanthrenes was discussed. A formal synthesis of tanshinone I was also studied. Natural products that contain a naphthalene or phenanthrene nucleus often exhibit biological activity, which makes them attractive targets in organic synthesis. The results showed that the reaction can be proceed through at least two different pathways.
A novel synthesis subtituted naphthalenes
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Ainanda L.
, p. 893 - 896 (2007/10/03)
Irradiation of 2-allylated acylbenzenes in DMF in the presence of potassium tert-butoxice constitutes a novel synthesis of substituted naphthalenes, including arylnaphthalenes. Typical examples including the conversions (1) → (2), (8) → (11) and (15) → (16).
