188439-52-3Relevant academic research and scientific papers
Facile synthesis of 2,2'-dichalcogenobis (N-alkyl/aryl benzenesulfonamides) from N-substituted benzenesulfonamides and the emergence of 2-alkyl 1,3,2-benzothiaselenazole 1,1 dioxides. Ebselen analogues
Mhizha, Sungano
, p. 17751 - 17760 (1997)
A one pot synthesis of 2-2'-diselenobis/ditellurobis(N-alkyl/aryl benzenesulfonamides) 4a-h from N-alkyl/aryl benzenesulfonamides is elaborated. The first cyclization of 2-2'-diselenobis (N-methyl benzenesulfonamide) 4a into 2-methyl-1,3,2-benzothiaselenazole 1,1 dioxide (5a) using 3-chloroperoxybenzoic acid is described. Compounds 4a-h and 5a and d act as a new class of biologically active compounds.
The reactions of 2-(bromoseleno)benzenesulfonyl chloride with primary amines toward 2,2′-diselenobis(benzenesulfonamides) and 1,3,2-benzothiaselenazole 1,1-dioxides: New oxygen-transfer agents, antimicrobials and virucides
Potaczek,Giurg,Kloc,Maliszewska,Piasecki,Pietka,Mlochowski
, p. 687 - 697 (2007/10/03)
The reaction of title compound 6 with primary aliphatic or aromatic amines was investigated. The products were 2,2′-diselenobis(benzenesulfonamides) (4) accompanied in some cases by 1,3,2-benzothiaselenazole 1,1 -dioxides (3). Exceptionally, when aniline was a reagent, 2-(sulfamoylphenyl) phenylselenenylanilide was produced. These results are interpreted in the light of the proposed mechanisms. The compounds 3 and 4 exhibited catalytic activity in hydroperoxide oxidation of cyclohexanone (12) and 1-naphthaldehyde N,N-dimethylhydrazone (17). Although they were inactive against patogenic bacteria and fungi an appreciable antiviral activity against HSV-1 and EMCV of the compounds 3b, 3c and 4b was observed.
Synthesis of organoselenium sulfonamides as new potential cytokine inducers: 2,2'-Diselenobis(benzenesulfonamides) and 1,3,2- benzothiaselenazolone 1,1-dioxides
Kloc, Krystian,Mlochowski, Jacek
, p. 67 - 71 (2007/10/03)
A convenient method for the synthesis of 2,2'- diselenobis(benzenesulfonamides) 4 and 2-substituted 1,3,2- benzothiaselenazole 1,1-dioxides 2, has been elaborated. It is based on the conversion of 2-aminobenzenesulfonic acid into bis[2-(chlorosulfonyl)phe
