188727-59-5

Basic information

• Product Name: 3-Pyrrolidinecarboxylic acid, 3-[(methylamino)carbonyl]-5-oxo-1-(phenylmethyl)-, ethyl ester
• CAS NO: 188727-59-5
• Molecular Formula: C16H20N2O4
• Molecular Weight: 304.346
• Mol File: 188727-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyrrolidinecarboxylic acid, 3-[(methylamino)carbonyl]-5-oxo-1-(phenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinecarboxylic acid, 3-[(methylamino)carbonyl]-5-oxo-1-(phenylmethyl)-, ethyl ester(188727-59-5)
• EPA Substance Registry System: 3-Pyrrolidinecarboxylic acid, 3-[(methylamino)carbonyl]-5-oxo-1-(phenylmethyl)-, ethyl ester(188727-59-5)

Safety Data

• Hazardous Substances Data: 188727-59-5(Hazardous Substances Data)

Upstream product

• 135380-25-5 diethyl 1-benzyl-5-oxopyrrolidine-3,3-dicarboxylate 
• 74-89-5 methylamine 
• 162686-34-2 monoethyl 1-benzyl-5-oxopyrrolidine-3,3-dicarboxylate 

Downstream Products

• 188727-64-2 (1-Benzyl-3-fluoromethyl-pyrrolidin-3-ylmethyl)-methyl-amine 
• 188727-62-0 1-Benzyl-3-fluoromethyl-5-oxo-pyrrolidine-3-carboxylic acid methylamide 
• 188727-60-8 1-Benzyl-3-hydroxymethyl-5-oxo-pyrrolidine-3-carboxylic acid methylamide 

Relevant articles and documents

Synthesis and structural optimization of 7-(3,3-disubstituted-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8 -methoxy-4-oxo-3-quinolinecarboxylic acids as antibacterial agents

A series of the titled compounds were synthesized and tested for antibacterial activities in comparison with typical fluoroquinolones. (S)-3-Aminomethyl-3-fluoromethyl derivative (Y-688) was confirmed to be optimal because of being most active especially against Gram-positive bacteria including fluoroquinolone-resistant strains and showing high photostability.