188743-65-9

Upstream product

• 14389-86-7 2-benzyloxybenzoic acid 
• 60022-62-0 L-serine benzyl ester hydrochloride 
• 119-36-8 methyl salicylate 
• 4349-62-6 2-benzyloxybenzoyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 188743-67-1 (4S)-benzyl 2-[2-(benzyloxy)phenyl]-Δ²-1,3-oxazoline-4-carboxylate 
• 370590-36-6 methyl (4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazole-4-carboxylate 
• 1378417-05-0 (2R)-6-formamido-2-[(4S)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoic acid 
• 1378417-02-7 (2S)-6-formamido-2-[(4R)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoic acid 
• 1378416-99-9 (2S)-6-formamido-2-[(4S)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoic acid 
• 1378235-14-3 (2R)-benzyl 6-formamido-2-[(4S)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoate 
• 1378235-13-2 (2S)-benzyl 6-formamido-2-[(4R)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoate 
• 1378235-11-0 (2S)-benzyl 6-formamido-2-[(4S)-2-(2-hydroxyphenyl)-Δ²-1,3-oxazoline-4-carboxamido]hexanoate 
• 188743-83-1 (S)-6-[Hexadecanoyl-(2-trimethylsilanyl-ethoxymethoxy)-amino]-2-{[(S)-2-(2-hydroxy-phenyl)-4,5-dihydro-oxazole-4-carbonyl]-amino}-hexanoic acid methyl ester 
• 188743-88-6 (S)-6-[Hexadecanoyl-(2-trimethylsilanyl-ethoxymethoxy)-amino]-2-{[(S)-2-(2-hydroxy-phenyl)-4,5-dihydro-oxazole-4-carbonyl]-amino}-hexanoic acid 
• 188743-71-7 (S)-6-(Hexadecanoyl-hydroxy-amino)-2-{[(S)-2-(2-hydroxy-phenyl)-4,5-dihydro-oxazole-4-carbonyl]-amino}-hexanoic acid methyl ester 
• 210548-01-9 (S)-6-(Hexadecanoyl-hydroxy-amino)-2-{[(S)-2-(2-hydroxy-phenyl)-4,5-dihydro-oxazole-4-carbonyl]-amino}-hexanoic acid 
• 155880-02-7 (4S)-2-[2-hydroxyphenyl]-Δ²-1,3-oxazoline-4-carboxylic acid 

Relevant academic research and scientific papers

Structure-activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters

During the syntheses and studies of natural iron chelators (mycobactins), we serendipitously discovered that a simple, small molecule, oxazoline-containing intermediate 3 displayed surprising anti-tuberculosis activity (MIC of 7.7?μM, average). Herein we

Total synthesis of a mycobactin S, a siderophore and growth promoter of Mycobacterium Smegmatis, and determination of its growth inhibitory activity against Mycobacterium tuberculosis

A general total synthesis of mycobactins, represented by a mycobactin S, was achieved by a convergent approach. Two hydroxamic acid residues, 28 and 40b, were prepared from commercially available N(α)-Cbz-L-lysine via dimethyldioxirane oxidations. Cycliza