4349-62-6Relevant articles and documents
Synthesis and preliminary biological evaluations of 5'-substituted derivatives of uridine as glycosyltransferase inhibitors
Paszkowska, Jadwiga,Kral, Katarzyna,Bieg, Tadeusz,Nawrot, Urszula,Szeja, Wieslaw,Wandzik, Ilona
, p. 8018 - 8027 (2013)
New derivatives of uridine which contain a β-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1-4 showed no activity against bovine milk β-1,4-galactosyltransferase I at concentrations up to 2.0 mM and were not
Capsaicine derivatives, preparation method of capsaicine derivatives and application of capsaicine derivatives in preparation of drugs for cardiovascular diseases
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Paragraph 0038-0041, (2020/12/05)
The invention provides capsaicine derivatives, a preparation method of the capsaicine derivatives and an application of the capsaicine derivatives in preparation of drugs for cardiovascular diseases.A compound has a structure as shown in a general formula
Metal-free Synthesis of Spiro-2,2′-benzo[b]furan-3,3′-ones via PhI(OAc)2-Mediated Cascade Spirocyclization
Xing, Qingyu,Liang, Huiyuan,Bao, Mingmai,Li, Xuemin,Zhang, Jingran,Bi, Tianhao,Zhang, Yilin,Xu, Jun,Du, Yunfei,Zhao, Kang
, p. 4669 - 4673 (2019/09/17)
Treating the benzyl protected 3-hydroxy-1,3-bis(2-hydroxyphenyl)prop-2-en-1-ones solely with PhI(OAc)2 (PIDA) in DCE at room temperature readily furnished the seldom studied spiro-2,2′-benzo[b]furan-3,3′-ones in satisfactory to excellent yields. The hypervalent iodine reagent enables the metal-free cascade spirocyclization resulting in the dual oxidative C?O bond formation. (Figure presented.).