188751-54-4

Basic information

• Product Name: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) ester
• Synonyms: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) ester;1-(tert-Butoxycarbonyl)-1H-indole-5-carboxylic acid
• CAS NO: 188751-54-4
• Molecular Formula: C14H15NO4
• Molecular Weight: 261.2732
• Mol File: 188751-54-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) ester(188751-54-4)
• EPA Substance Registry System: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) ester(188751-54-4)

Safety Data

• Hazardous Substances Data: 188751-54-4(Hazardous Substances Data)

Usage

General Description

1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) ester is a chemical compound with the molecular formula C17H19NO4. It is an ester derivative of indole-1,5-dicarboxylic acid, and it is commonly used in organic synthesis and pharmaceutical research. 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) ester has potential applications in the development of new drugs and pharmaceuticals due to its unique structure and properties. It is a solid compound with a molecular weight of 297.34 g/mol, and it is typically used as a reagent or intermediate in organic chemistry reactions. Overall, 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) ester is a versatile chemical compound with potential applications in various fields, including medicine and drug development.

Upstream product

• 124-38-9 carbon dioxide 
• 182344-70-3 5-bromo-indole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 272438-11-6 1-tert-butoxycarbonyl-5-methoxycarbonylindole 
• 777061-36-6 1,1-dimethylethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 

Relevant articles and documents

Method for preparing aromatic carboxylic acid compound

The invention discloses a method for preparing an aromatic carboxylic acid compound. The method comprises the following steps: 1) heating carbon dioxide and hydrosilane in the presence of a copper catalyst in a reaction medium A; and 2) adding a reaction medium B, aryl halide, a palladium catalyst and a base to the reaction mixture in the step 1), sealing the reaction system, and performing a heating reaction. The method has the advantages that raw materials are simple and easy to obtain, the raw materials are cheap and stable, the catalyst is common, easy to obtain and stable, the reaction conditionsaremild, the aftertreatment is simple, the yield is high, and the like.

Visible-Light-Driven Carboxylation of Aryl Halides by the Combined Use of Palladium and Photoredox Catalysts

A highly useful, visible-light-driven carboxylation of aryl bromides and chlorides with CO2 was realized using a combination of Pd(OAc)2 as a carboxylation catalyst and Ir(ppy)2(dtbpy)(PF6) as a photoredox catalyst. This carboxylation reaction proceeded in high yields under 1 atm of CO2 with a variety of functionalized aryl bromides and chlorides without the necessity of using stoichiometric metallic reductants.