272438-11-6

Basic information

• Product Name: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) 5-Methyl ester
• Synonyms: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) 5-Methyl ester;1-tert-butyl 5-Methyl 1H-indole-1,5-dicarboxylate;Methyl 1-BOC-indole-5-carboxylate
• CAS NO: 272438-11-6
• Molecular Formula: C15H17NO4
• Molecular Weight: 275.29978
• Mol File: 272438-11-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) 5-Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) 5-Methyl ester(272438-11-6)
• EPA Substance Registry System: 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-diMethylethyl) 5-Methyl ester(272438-11-6)

Safety Data

• Hazardous Substances Data: 272438-11-6(Hazardous Substances Data)

Usage

General Description

1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) 5-methyl ester is a chemical compound that belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. It is commonly used in the synthesis of pharmaceuticals and has potential applications in the field of medicine. 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) 5-methyl ester is also used as a building block in the synthesis of various organic compounds due to its versatile reactivity and functional group compatibility. Additionally, it has demonstrated biological activity in pre-clinical studies, making it a potentially valuable tool for drug discovery and development. Overall, 1H-Indole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl) 5-methyl ester is a versatile chemical compound with various potential applications in the pharmaceutical and medicinal fields.

Upstream product

• 188751-54-4 1-(tert-butoxycarbonyl)-1H-indole-5-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 182344-70-3 5-bromo-indole-1-carboxylic acid tert-butyl ester 
• 1011-65-0 5-methoxycarbonylindole 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 279255-90-2 tert-butyl 5-(hydroxymethyl)-1H-indole-1-carboxylate 

Relevant articles and documents

Visible-Light-Driven Carboxylation of Aryl Halides by the Combined Use of Palladium and Photoredox Catalysts

A highly useful, visible-light-driven carboxylation of aryl bromides and chlorides with CO2 was realized using a combination of Pd(OAc)2 as a carboxylation catalyst and Ir(ppy)2(dtbpy)(PF6) as a photoredox catalyst. This carboxylation reaction proceeded in high yields under 1 atm of CO2 with a variety of functionalized aryl bromides and chlorides without the necessity of using stoichiometric metallic reductants.

HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE

To provide a novel compound which has S1P receptor agonistic activity, exhibits excellent immunosuppressing effect, gives less adverse side effects, and can be orally administered. The invention provides a compound represented by general formula (I) (wherein A is a single bond, -O-, or - CH2-; R1 represents a hydrogen atom or a C1-C6 alkyl group, and V represents any one group selected from among the following groups (1) to (3) : (1) -G1-, (2) -G2-N(R2) -G3-, and (3) a group represented by formula 2, wherein each of Z1 and Z2 represents a hydrogen atom or a C1-C6 alkyl group, Z3 represents a hydrogen or the like, Q represents -CH2-O- or the like, and Y represents a group represented by foumula 3, a salt thereof, or a solvate thereof.