188755-65-9Relevant academic research and scientific papers
Synthesis of Chiral Phosphorus Reagents and Their Catalytic Activity in Asymmetric Borane Reduction of N-Phenyl Imine of Acetophenone
Kangying, Li,Zhenghong, Zhou,Guofeng, Zhao,Chuchi, Tang
, p. 546 - 550 (2003)
Eleven chiral trivalent or quatrivalent phosphorus reagents were synthesized starting from L-proline, D-camphor, (+)- or (-)-1,1'-binaphthalene-2,2'-diol, (-)-α-phenylethylamine, etc. and their application as catalysts in asymmetric borane reduction of N-
Studies on chiral thiophosphoric acids and their derivatives 16. - The asymmetric cyclization of L-(+)-prolinol with (thio)phosphoro(-no)dichloridates
He, Zheng-Jie,Wang, You-Ming,Tang, Chu-Chi
, p. 59 - 66 (2007/10/03)
The cyclizations of L-(+)-prolinol 5 with (thio)phosphoro(-no)dichloridates 6 give 1,2,3-azaphosphaoxabicyclo[3.3.0]octanes 7 consisting of unequal amounts of diastereoisomers, eight pairs of which have been successfully resolved by silica gel column chromatography or recrystallization. The influences of reaction temperature, solvent and substrate concentration upon the asymmetric induction have also been investigated.
