188846-99-3 Usage
Description
1-N-CBZ-3-CYANO-PYRROLIDINE is a chemical compound that serves as a crucial building block in the pharmaceutical industry, used for the synthesis of a variety of drugs. It is a derivative of pyrrolidine, a heterocyclic organic compound, featuring a carbobenzyloxy (CBZ) group at the 1 position and a cyano group at the 3 position. Known for its versatile reactivity, 1-N-CBZ-3-CYANO-PYRROLIDINE is instrumental in the preparation of pharmaceutical intermediates and bioactive compounds, contributing to the development of new drugs and pharmaceutical products. Its unique structure and reactivity make it a significant component in the advancement of novel therapeutic agents.
Uses
Used in Pharmaceutical Industry:
1-N-CBZ-3-CYANO-PYRROLIDINE is used as a key building block for the synthesis of various drugs, leveraging its versatile reactivity to facilitate the creation of pharmaceutical intermediates and bioactive compounds. Its incorporation into drug development processes is driven by its potential to enhance the efficacy and properties of new therapeutic agents.
Used in Drug Development:
1-N-CBZ-3-CYANO-PYRROLIDINE is utilized as a component in the development of novel therapeutic agents, capitalizing on its unique structure to improve the pharmacological profiles of new drugs. Its presence in the synthesis process can lead to the discovery of innovative treatments for various medical conditions.
Used in Research and Development:
In the realm of research and development, 1-N-CBZ-3-CYANO-PYRROLIDINE is employed as a valuable tool for exploring new chemical reactions and pathways, contributing to the advancement of pharmaceutical science and the discovery of more effective drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 188846-99-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,8,4 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 188846-99:
(8*1)+(7*8)+(6*8)+(5*8)+(4*4)+(3*6)+(2*9)+(1*9)=213
213 % 10 = 3
So 188846-99-3 is a valid CAS Registry Number.
188846-99-3Relevant articles and documents
Nitrilase-catalyzed enantioselective synthesis of pyrrolidine- And piperidinecarboxylic acids
Winkler, Margit,Meischler, Dorith,Klempier, Norbert
, p. 1475 - 1480 (2008/09/16)
The enantioselective synthesis of the nonproteinogenic amino acids β-proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerably reducing the multiple steps generally required. Amide formation is also observed for specific heterocyclic nitriles.
Non-classical antifolates
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, (2008/06/13)
Compounds of the formula: in which:, Q is -OH or -NH2;, A is -CH2-, -CH2CH2-, -O-, or -S-;, -Ar- is a divalent aromatic ring;, W is -CO- or -SO2; and, Z is: (A) an α-amino acid group of the formula (B
