188883-57-0

Basic information

• Product Name: (R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER
• Synonyms: (R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER
• CAS NO: 188883-57-0
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171.238
• Mol File: 188883-57-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER(188883-57-0)
• EPA Substance Registry System: (R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER(188883-57-0)

Safety Data

• Hazardous Substances Data: 188883-57-0(Hazardous Substances Data)

Usage

General Description

"(R)-PIPERIDIN-3-YL-ACETIC ACID ETHYL ESTER" is a chemical compound, which notably belongs to the category of organic compounds known as piperidines. Piperidine is a heterocyclic organic compound that consists of a six-membered ring with five carbons and one nitrogen. It is crucial in the structure of many natural compounds, including alkaloids and vitamins. When in an ethyl ester format, the compound contains a carboxylic acid in which the hydrogen of the hydroxyl (OH) group has been replaced by an ethyl group. The "(R)" in the name indicates the direction in which the molecules of this compound rotate light, which can have implications on its chemical properties and practical applications. As is the case with most esters, this compound likely has a distinctive smell and could potentially be used in a variety of industrial applications, including solvent, chemical synthesis, or as a possible intermediate in pharmaceuticals; however, its specific uses and potential toxicity have not been detailed.

Upstream product

• 64995-88-6 ethyl 2-(piperidin-3-yl)acetate 
• 6419-36-9 3-pyridineacetic acid hydrochloride 
• 3423-47-0 3-(2-ethoxy-2-oxoethyl)pyridin-1-ium-1-olate 
• 1232140-16-7 1-benzyl-3-ethoxycarbonylmethyl-pyridinium chloride 
• 39931-77-6 pyridin-3-yl-acetic acid ethyl ester 
• 912940-89-7 2-[(3R)-1-[(tert-butoxy)carbonyl]piperidin-3-yl]acetic acid 

Downstream Products

• 1265750-10-4 ethyl 2-((R)-1-((S)-2-(tert-butyldimethylsilyloxy)-2-(4-((Z)-N'-hydroxycarbamimidoyl)phenyl)ethyl)piperidin-3-yl)acetate 
• 1265323-61-2 ethyl 2-((R)-1-((S)-2-(tert-butyldimethylsilyloxy)-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidin-3-yl)acetate 
• 1265323-31-6 2-((R)-1-((S)-2-hydroxy-2-(4-(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidin-3-yl)acetic acid 
• 1265323-36-1 2-((R)-1-((S)-2-(4-(5-(1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl)phenyl)-2-hydroxyethyl)piperidin-3-yl)acetic acid 
• 1265323-60-1 ethyl 2-((R)-1-((S)-2-(tert-butyldimethylsilyloxy)-2-(4-cyanophenyl)ethyl)piperidin-3-yl)acetate 
• 1233200-48-0 (R)-piperidin-3-yl-acetic acid ethyl ester hydrochloride 
• 1265323-57-6 ethyl 2-((R)-1-((R)-2-(4-cyanophenyl)-2-hydroxyethyl)-piperidin-3-yl)acetate 
• 1265323-56-5 ethyl 2-((R)-1-((S)-2-(4-cyanophenyl)-2-hydroxyethyl)-piperidin-3-yl)acetate 

Relevant articles and documents

Practical and scalable synthesis of ethyl (R)-piperidine-3-acetate

A practical and scalable synthesis of ethyl (R)-piperidine-3-acetate was achieved from commercially available 3-pyridylacetic acid in 76% overall yield. The practical synthesis was demonstrated on 100-g scale. One-pot reductive N-ethylation of the pyridinium salt with acetonitrile gave an N-ethyl piperidine derivative. Copyright Taylor & Francis Group, LLC.