1233200-48-0 Usage
Uses
Used in Pharmaceutical Synthesis:
(R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride is used as a chiral building block for the synthesis of pharmaceuticals and other organic compounds. Its specific (R)-enantiomer form provides a crucial advantage in the development of enantioselective drugs, ensuring the desired biological activity and minimizing potential side effects.
Used in Metal-Catalyzed Reactions:
In the field of organic chemistry, (R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride serves as a ligand in metal-catalyzed reactions. Its presence can enhance the selectivity and efficiency of these reactions, leading to the production of desired enantiomers with improved yields.
Used in Organic Synthesis:
(R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride is also employed as a reagent in various organic synthesis processes. Its ability to participate in a range of chemical reactions, such as esterification, amidation, and acylation, makes it a valuable tool for the preparation of complex organic molecules.
Used in Research and Development:
The hydrochloride salt form of (R)-Ethyl 2-(piperidin-3-yl)acetic acid enhances its solubility in water, making it easier to handle and store. This property is particularly beneficial in research and development settings, where the compound can be readily incorporated into experimental designs and used to explore new chemical reactions and applications.
Overall, (R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride is a versatile and valuable chemical compound with applications spanning across pharmaceutical synthesis, metal-catalyzed reactions, organic synthesis, and research and development. Its unique properties and reactivity make it an essential component in the development of new drugs and organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1233200-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,3,2,0 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1233200-48:
(9*1)+(8*2)+(7*3)+(6*3)+(5*2)+(4*0)+(3*0)+(2*4)+(1*8)=90
90 % 10 = 0
So 1233200-48-0 is a valid CAS Registry Number.
1233200-48-0Relevant academic research and scientific papers
Practical and scalable synthesis of ethyl (R)-piperidine-3-acetate
Zhu, Ying-Guang,Kan, Hong-Zhu,Jiang, Li-Qin,Hu, Wen-Hao
, p. 1137 - 1145 (2012/05/05)
A practical and scalable synthesis of ethyl (R)-piperidine-3-acetate was achieved from commercially available 3-pyridylacetic acid in 76% overall yield. The practical synthesis was demonstrated on 100-g scale. One-pot reductive N-ethylation of the pyridinium salt with acetonitrile gave an N-ethyl piperidine derivative. Copyright Taylor & Francis Group, LLC.