1232140-16-7Relevant articles and documents
Practical and scalable synthesis of ethyl (R)-piperidine-3-acetate
Zhu, Ying-Guang,Kan, Hong-Zhu,Jiang, Li-Qin,Hu, Wen-Hao
, p. 1137 - 1145 (2012)
A practical and scalable synthesis of ethyl (R)-piperidine-3-acetate was achieved from commercially available 3-pyridylacetic acid in 76% overall yield. The practical synthesis was demonstrated on 100-g scale. One-pot reductive N-ethylation of the pyridinium salt with acetonitrile gave an N-ethyl piperidine derivative. Copyright Taylor & Francis Group, LLC.