188883-58-1 Usage
Uses
(S)-Ethyl 2-(Piperidin-3-yl)acetate is used as a reagent in the synthesis of phenylethylaminopyrimidinylpiperidine derivatives which can be used as prostaglandin D2 receptor antagonists.
Check Digit Verification of cas no
The CAS Registry Mumber 188883-58-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,8,8 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 188883-58:
(8*1)+(7*8)+(6*8)+(5*8)+(4*8)+(3*3)+(2*5)+(1*8)=211
211 % 10 = 1
So 188883-58-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H17NO2.ClH/c1-2-12-9(11)6-8-4-3-5-10-7-8;/h8,10H,2-7H2,1H3;1H
188883-58-1Relevant articles and documents
Practical and scalable synthesis of ethyl (R)-piperidine-3-acetate
Zhu, Ying-Guang,Kan, Hong-Zhu,Jiang, Li-Qin,Hu, Wen-Hao
, p. 1137 - 1145 (2012/05/05)
A practical and scalable synthesis of ethyl (R)-piperidine-3-acetate was achieved from commercially available 3-pyridylacetic acid in 76% overall yield. The practical synthesis was demonstrated on 100-g scale. One-pot reductive N-ethylation of the pyridinium salt with acetonitrile gave an N-ethyl piperidine derivative. Copyright Taylor & Francis Group, LLC.
