188918-39-0

Usage

Uses

Used in Pharmaceutical Industry:
cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its Boc protecting group allows for selective deprotection and coupling reactions, facilitating the construction of complex peptide sequences and drug molecules.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid serves as a versatile building block for the design and synthesis of novel bioactive molecules. Its unique structure and properties enable the development of potential drug candidates with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability.
Used in Organic Synthesis:
cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid is utilized as a valuable starting material in organic synthesis for the preparation of various organic compounds. Its Boc protecting group allows for controlled reactions and selective transformations, making it an ideal choice for the synthesis of complex organic molecules with specific functional groups and stereochemistry.
Overall, cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid is a promising chemical compound with diverse applications in the pharmaceutical, medicinal chemistry, and organic synthesis industries. Its unique structure, properties, and versatility make it an essential component in the development of innovative drug candidates and organic compounds.

Upstream product

• 188918-44-7 tert-butyl [(1R,3S)-3-acetyl-2,2-dimethylcyclobutyl]carbamate 
• 1379185-80-4 methyl 3-amino-2,2-dimethylcyclobutanecarboxylate 
• 78685-51-5 2,2-dimethyl-3-oxo-cyclobutanecarboxylic acid methyl ester 
• 1261253-74-0 (1S,3R)-benzyl 3-acetamido-2,2-dimethylcyclobutanecarboxylate 
• 1261253-73-9 (1S,3R)-benzyl 3-acetyl-2,2-dimethylcyclobutanecarboxylate 
• 288848-24-8 (1S,3R)-3-acetyl-2,2-dimethylcyclobutane carboxylic acid 
• 80-57-9 (-)-Verbenone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 308287-83-4 (1S,3R)-(+)-3-(2-Acetamido)-2,2-dimethylcyclobutanecarboxylic acid 
• 22571-78-4 (+)-cis-pinononoic acid 
• 1313358-57-4 (1R,3S)-methyl 3-(tert-butoxycarbonylamino)-2,2-dimethylcyclobutanecarboxylate 
• 1017279-78-5 benzyl (1S,3R)-3-methoxycarbonyl-2,2-dimethylcyclobutyl-1-carbamate 
• 1017279-76-3 (1R,3S)-3-(((benzyloxy)carbonyl)amino)-2,2-dimethylcyclobutan-1-carboxylic acid 
• 1017279-96-7 benzyl (1S,3R)-3-acetyl-2,2-dimethylcyclobutyl-1-carbamate 

Downstream Products

• 527751-18-4 (1S,3R)-3-amino-2,2-dimethylcyclobutan-1-carboxylic acid 

Relevant academic research and scientific papers

1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE

The purpose of the present invention is to provide a compound having PIM inhibitory activity. Examples of the present invention include 1,3,4-oxadiazolone compounds represented by the following formula [1], and pharmaceutically acceptable salts, and solvates thereof. The compounds of the present invention have PIM inhibitory activity. In addition, since the compounds of the present invention have PIM inhibitory activity, the compounds of the present invention are useful as therapeutic agents for systemic lupus erythematosus, lupus nephritis, etc.

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS

The invention relates to novel lupeol-type triterpene derivatives and related compounds, and pharmaceutical compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.

NOVEL AZA-PEPTIDES CONTAINING 2,2-DISUBSTITUTED CYCLOBUTYL AND/OR SUBSTITUTED ALKOXY BENZYL DERIVATIVES AS ANTIVIRALS

The present invention relates to novel aza-peptides containing 2,2-disubstituted 5 cyclobutyl and/or substituted alkoxy benzyl derivatives of formula (I) and compositions for inhibiting Human Immunodeficiency Virus (HIV) and process for making the compounds.

Chiral 1,3-cyclobutane amino acids: Syntheses and extended conformations

Optically active samples of the N-protected 1,3-cyclobutane amino acids 1 and 2 were prepared from α-pinene. The synthesis of 1 is enantiodivergent insofar as both optical antipodes of the product can be prepared from the same α-pinene enantiomer. Single crystal X-ray diffraction studies of derivatives of 1 reveal these compounds can have extended conformations.