188918-39-0

Basic information

• Product Name: cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid
• Synonyms: cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid;(1R,3S)-3-((tert-Butoxycarbonyl)amino)-2,2-dimethylcyclobutanecarboxylic acid;cis-3-(Boc-amino)-2,2-dimethylcyclobutanecarboxylic acid - A11844
• CAS NO: 188918-39-0
• Molecular Formula: C12H21NO4
• Molecular Weight: 243.29944
• Mol File: 188918-39-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid(188918-39-0)
• EPA Substance Registry System: cis-3-(Boc-aMino)-2,2-diMethylcyclobutanecarboxylic acid(188918-39-0)

Safety Data

• Hazardous Substances Data: 188918-39-0(Hazardous Substances Data)

Usage

General Description

Cis-3-(Boc-amino)-2,2-dimethylcyclobutanecarboxylic acid is a chemical compound that belongs to the class of cyclobutanecarboxylic acids. It is a derivative of amino acids and features a tert-butoxycarbonyl (Boc) protecting group attached to the amino group. The cis configuration of the cyclobutane ring and the presence of the Boc group makes it a versatile building block in organic synthesis, particularly in the production of peptide and pharmaceutical compounds. Its unique structure and properties make it valuable in the field of medicinal chemistry and drug development.

Upstream product

• 1379185-80-4 methyl 3-amino-2,2-dimethylcyclobutanecarboxylate 
• 78685-51-5 2,2-dimethyl-3-oxo-cyclobutanecarboxylic acid methyl ester 
• 1313358-57-4 (1R,3S)-methyl 3-(tert-butoxycarbonylamino)-2,2-dimethylcyclobutanecarboxylate 
• 1017279-78-5 benzyl (1S,3R)-3-methoxycarbonyl-2,2-dimethylcyclobutyl-1-carbamate 
• 1017279-76-3 (1R,3S)-3-(((benzyloxy)carbonyl)amino)-2,2-dimethylcyclobutan-1-carboxylic acid 
• 1017279-96-7 benzyl (1S,3R)-3-acetyl-2,2-dimethylcyclobutyl-1-carbamate 
• 1017279-74-1 (1R,3S)-3-azidocarbonyl-2,2-dimethylcyclobutyl methyl ketone 
• 288848-24-8 (1S,3R)-3-acetyl-2,2-dimethylcyclobutane carboxylic acid 
• 80-57-9 (-)-Verbenone 
• 136780-45-5 methyl (1S,3R)-3-acetyl-2,2-dimethylcyclobutanecarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1261253-74-0 (1S,3R)-benzyl 3-acetamido-2,2-dimethylcyclobutanecarboxylate 
• 1261253-73-9 (1S,3R)-benzyl 3-acetyl-2,2-dimethylcyclobutanecarboxylate 
• 308287-83-4 (1S,3R)-(+)-3-(2-Acetamido)-2,2-dimethylcyclobutanecarboxylic acid 

Downstream Products

• 527751-18-4 (1S,3R)-3-amino-2,2-dimethylcyclobutan-1-carboxylic acid 

Relevant articles and documents

1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE

The purpose of the present invention is to provide a compound having PIM inhibitory activity. Examples of the present invention include 1,3,4-oxadiazolone compounds represented by the following formula [1], and pharmaceutically acceptable salts, and solvates thereof. The compounds of the present invention have PIM inhibitory activity. In addition, since the compounds of the present invention have PIM inhibitory activity, the compounds of the present invention are useful as therapeutic agents for systemic lupus erythematosus, lupus nephritis, etc.

NOVEL AZA-PEPTIDES CONTAINING 2,2-DISUBSTITUTED CYCLOBUTYL AND/OR SUBSTITUTED ALKOXY BENZYL DERIVATIVES AS ANTIVIRALS

The present invention relates to novel aza-peptides containing 2,2-disubstituted 5 cyclobutyl and/or substituted alkoxy benzyl derivatives of formula (I) and compositions for inhibiting Human Immunodeficiency Virus (HIV) and process for making the compounds.

Chiral 1,3-cyclobutane amino acids: Syntheses and extended conformations

Optically active samples of the N-protected 1,3-cyclobutane amino acids 1 and 2 were prepared from α-pinene. The synthesis of 1 is enantiodivergent insofar as both optical antipodes of the product can be prepared from the same α-pinene enantiomer. Single crystal X-ray diffraction studies of derivatives of 1 reveal these compounds can have extended conformations.