188945-28-0Relevant academic research and scientific papers
Proton exchange and chemoselectivity in metal cation and hydroxide ion hydrolyses of phosphonoacetate diesters
Moss, Robert A.,Gong, Paul K.
, p. 7845 - 7848 (2003)
Phosphonoacetate diesters exhibit base catalyzed D/H proton exchange and C-OR esterolysis, as well as (acidic) hydrolyses mediated by Th4+ and Zr4+ ions.
Highly Selective Synthesis of Z-Unsaturated Esters by Using New Horner-Emmons Reagents, Ethyl (Diarylphosphono)acetates
Ando, Kaori
, p. 1934 - 1939 (2007/10/03)
New Horner-Emmons reagents, ethyl (diarylphosphono)acetates 1, were prepared from triethyl phosphonoacetate, PCl5 the corresponding phenols. The reaction of 1 with several kinds of aldehydes in the presence of Triton B or NaH in THF solvent revealed that these reagents are useful for the synthesis of Z-unsaturated esters. Among the reagents examined, ethyl(di-o-tolylphosphono)-, [bis(o-ethylphenyl)phosphonol-, and [bis(o-isopropylphenyl)phosphono]acetates (1k-m) were found to be the most effective, giving Z-unsaturated esters with 93-99% selectivity.
