188990-08-1

Basic information

• Product Name: 2-Propenoic acid, 3-(2-iodophenyl)-, methyl ester
• CAS NO: 188990-08-1
• Molecular Formula: C10H9IO2
• Molecular Weight: 288.085
• Mol File: 188990-08-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(2-iodophenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(2-iodophenyl)-, methyl ester(188990-08-1)
• EPA Substance Registry System: 2-Propenoic acid, 3-(2-iodophenyl)-, methyl ester(188990-08-1)

Safety Data

• Hazardous Substances Data: 188990-08-1(Hazardous Substances Data)

Upstream product

• 26260-02-6 2-iodobenzaldehyde 

Downstream Products

• 85-01-8 phenanthrene 
• 146967-87-5 methyl 2-(9H-fluoren-9-ylidene)acetate 
• 1073950-80-7 methyl {2-[(2,5-difluorophenyl)amino]-3-oxo-2,3-dihydro-1H-isoindol-1-yl}acetate 
• 1073950-97-6 methyl (2-acetyl-4-oxo-3-phenyl-1,2,3,4-tetrahydrophthalazin-1-yl)acetate 
• 1073950-92-1 methyl (2-anilino-3-oxo-2,3-dihydro-1H-isoindol-1-yl)acetate 
• 1073951-15-1 methyl (4-oxo-3-phenyl-1,2,3,4-tetrahydrophthalazin-1-yl)acetate 
• 88460-63-3 methyl [2-(4-methoxyphenyl)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]acetate 

Relevant articles and documents

The ketene-surrogate coupling: Catalytic conversion of aryl iodides into aryl ketenes through ynol ethers

tert-Butoxyacetylene is shown to undergo Sonogashira coupling with aryl iodides to yield aryl-substituted tert-butyl ynol ethers. These intermediates participate in a [1,5]-hydride shift, which results in the extrusion of isobutylene and the generation of aryl ketenes. The ketenes are trapped in situ with multiple nucleophiles or undergo electrocyclic ring closure to yield hydroxynaphthalenes and quinolines.